"Col1a1" Related Products

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Recombinant Mouse Col1a1 protein, His-tagged

Cat.No.: Col1a1-08M
Product Overview: Recombinant Mouse Col1a1 fused with His tag was expressed in HEK293.
Description: This gene encodes the alpha-1 subunit of the fibril-forming type I collagen, the most abundant protein of bone, skin and tendon extracellular matrices. The encoded protein, in association with alpha-2 subunit, forms heterotrimeric type I procollagen that undergoes proteolytic processing during fibril formation. Mice lacking the encoded protein die in utero caused by the rupture of a major blood vessel. Transgenic mice expressing significantly lower levels of this gene exhibit morphological and functional defects in mineralized and non-mineralized connective tissue and, progressive loss of hearing.
Source: HEK293
Species: Mouse
Tag: His
Form: Tris-based buffer, 50% glycerol
Purity: >90% (SDS-PAGE)
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage: Store at -20 centigrade, for extended storage, conserve at -20 centigrade or -80 centigrade.
Gene Name: Col1a1 collagen, type I, alpha 1 [ Mus musculus ]
Official Symbol: Col1a1
Synonyms: COL1A1; collagen, type I, alpha 1; collagen alpha-1(I) chain; alpha-1 type 1 collagen; alpha-1 type I collagen; procollagen, type I, alpha 1; Cola1; Mov13; Cola-1; Mov-13; Col1a-1;
Gene ID: 12842
mRNA Refseq: NM_007742
Protein Refseq: NP_031768
MIM:
UniProt ID: P11087
Chromosome Location: 11 59.01 cM; 11 D
Pathway: Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Axon guidance, organism-specific biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Developmental Biology, organism-specific biosystem; ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem;
Function: extracellular matrix structural constituent; identical protein binding; platelet-derived growth factor binding; protein binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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