"Col1a1" Related Products

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Recombinant Mouse Col1a1 protein, His-tagged

Cat.No.: Col1a1-09M
Product Overview: Recombinant Mouse Col1a1(Lys1225~Val1453) fused with His tag at N-terminal was expressed in E. coli.
Description: This gene encodes the alpha-1 subunit of the fibril-forming type I collagen, the most abundant protein of bone, skin and tendon extracellular matrices. The encoded protein, in association with alpha-2 subunit, forms heterotrimeric type I procollagen that undergoes proteolytic processing during fibril formation. Mice lacking the encoded protein die in utero caused by the rupture of a major blood vessel. Transgenic mice expressing significantly lower levels of this gene exhibit morphological and functional defects in mineralized and non-mineralized connective tissue and, progressive loss of hearing
Source: E. coli
Species: Mouse
Tag : His
Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300
Molecular Mass: 28.0kDa
Protein length: Lys1225~Val1453
Endotoxin: <1.0EU per 1µg (determined by the LAL method)
Purity: > 95%
Applications: Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein
Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution: Reconstitute in PBS or others.
Gene Name: Col1a1 collagen, type I, alpha 1 [ Mus musculus ]
Official Symbol: Col1a1
Synonyms: COL1A1; collagen, type I, alpha 1; collagen alpha-1(I) chain; alpha-1 type 1 collagen; alpha-1 type I collagen; procollagen, type I, alpha 1; Cola1; Mov13; Cola-1; Mov-13; Col1a-1;
Gene ID: 12842
mRNA Refseq: NM_007742
Protein Refseq: NP_031768
UniProt ID: P11087
Chromosome Location: 11 59.01 cM; 11 D
Pathway: Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Axon guidance, organism-specific biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Developmental Biology, organism-specific biosystem; ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem;
Function: extracellular matrix structural constituent; identical protein binding; platelet-derived growth factor binding; protein binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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