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Active Recombinant Mouse Ctsb protein, His-tagged

Cat.No. : Ctsb-415M
Product Overview : Recombinant Mouse Ctsb(Met 1-Phe 339) fused with His tag at C-terminal was expressed in HEK293.
  • Specification
  • Gene Information
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Source : HEK293
Species : Mouse
Tag : His
Predicted N Terminal : His 18
Form : Lyophilized from sterile PBS, pH 7.41. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.2. Please contact us for any concerns or special requirements.
Bio-activity : Measured by its ability to cleave the fluorogenic peptide substrate Z-LR-AMC. The specific activity is >2,000 pmoles/min/μg.
Molecular Mass : The secreted recombinant mouse CTSB (pro form) consists of 333 amino acids and has a predicted molecular mass of 36.6 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm CTSB is approximately 35-43 kDa due to glycosylation.
Protein length : Met 1-Phe 339
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : >95 % as determined by SDS-PAGE
Stability : Samples are stable for up to twelve months from date of receipt at -70 centigrade
Storage : Store it under sterile conditions at -20 centigrade to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Shipping : In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Gene Name : Ctsb cathepsin B [ Mus musculus ]
Official Symbol : Ctsb
Synonyms : CTSB; cathepsin B; cathepsin B1; CB;
Gene ID : 13030
mRNA Refseq : NM_007798
Protein Refseq : NP_031824
MIM :
UniProt ID :
Chromosome Location : 14 D1; 14 33.24 cM
Pathway : Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; thyroid hormone biosynthesis, conserved biosystem;
Function : cysteine-type endopeptidase activity; cysteine-type peptidase activity; endopeptidase activity; hydrolase activity; kininogen binding; peptidase activity; peptide binding; protein complex binding; protein self-association;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How does CTSB affect extracellular matrix remodeling in conditions like osteoarthritis? 01/28/2022

CTSB affects extracellular matrix remodeling, relevant in joint diseases like osteoarthritis.

What role does CTSB play in the pathology of neurodegenerative diseases, such as Alzheimer's? 03/29/2020

CTSB is implicated in neurodegenerative diseases, potentially contributing to protein aggregation and neuronal damage.

How do alterations in CTSB expression or activity affect tissue repair and fibrosis? 04/26/2019

Variations in CTSB expression impact tissue repair processes and the development of fibrosis in various organs.

What are the mechanisms by which CTSB modulates apoptosis and cell survival? 09/26/2018

CTSB regulates apoptosis and cell survival, influencing cell fate decisions under stress or damage.

How does CTSB influence the tumor microenvironment and cancer progression? 08/16/2018

CTSB can influence cancer progression by modulating the tumor microenvironment and facilitating tumor cell invasion.

How does CTSB (Cathepsin B) contribute to protein degradation and lysosomal function? 04/01/2018

CTSB is involved in lysosomal protein degradation, essential for cellular waste disposal and recycling.

What is the impact of CTSB in inflammatory responses and immune cell activation? 01/04/2018

CTSB plays a role in inflammation, impacting immune cell function and inflammatory responses.

Customer Reviews (3)

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Reviews
08/08/2021

    Exceptional protein engineering services, our trusted research partner.

    07/13/2021

      Reliable protein crystallography, key for our structural biology research.

      11/15/2018

        Swift protein quantification, improves data reliability in our work.

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