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Recombinant Mouse Eif2ak2 protein, GST-tagged

Cat.No. : EIF2AK2-489M
Product Overview : Recombinant Mouse Eif2ak2 fused with GST tag was expressed in Insect cells.
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Description : Eif2ak2 played an important role in many functions.
Source : Insect cells
Species : Mouse
Tag : GST
Molecular Mass : 56.33KD (with GST tag)
AA Sequence : MSPILGYWKIKGLVQPTRLLLEYLE EKYEEHLYERDEGDKWRNKKFELGL EFPNLPYYIDGDVKLTQSMAIIRYI ADKHNMLGGCPKERAEISMLEGAVL DIRYGVSRIAYSKDFETLKVDFLSK LPEMLKMFEDRLCHKTYLNGDHVTH PDFMLYDALDVVLYMDPMCLDAFPK LVCFKKRIEAIPQIDKYLKSSKYIA WPLQGWQATFGGGDHPPKGFGQVFK AKHRIDGKRYAIKRVKYNTEKAEHE VQALAELNHVNIVQYHSCWEGVDYD PEHSMSDTSRYKTRCLFIQMEFCDK GTLEQWMRNRNQSKVDKALILDLYE QIVTGVEYIHSKGLIHRDLKPGNIF LVDERHIKIGDFGLATALENDGKSR TRRTGTLQYMSPEQLFLKHYGKEVD IFALGLILAELLHTCFTESEKIKFF ESLRKGDFSNDIFDNKEKSLLKKLL SEKPKDRPETSEILKTLAEWRNISE KKKRNTC
Storage : Short Term Storage at +4 centigrade, Long Term Storage at -20 centigrade to -80 centigrade. Avoid freeze/thaw cycles.
Concentration : 0.05 mg/ml
Gene Name : Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 [ Mus musculus ]
Official Symbol : Eif2ak2
Synonyms : EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2; interferon-induced, double-stranded RNA-activated protein kinase; p68 kinase; eIF-2 alpha; dsRNA-activated kinase; eIF-2A protein kinase 2; P1/eIF-2A protein kinase; protein kinase RNA-activated; T-cell viral integration site; tyrosine-protein kinase EIF2AK2; serine/threonine-protein kinase TIK; IFN- type I-induced and dsRNA-activated kinase; interferon-inducible RNA-dependent protein kinase; IFN-induced and double-stranded RNA-activated kinase; eukaryotic translation initiation factor 2 alpha kinase 2; protein kinase, interferon inducible double stranded RNA dependent; protein kinase, interferon-inducible double stranded RNA dependent; Pkr; Tik; Prkr; AI467567; AI747578; 2310047A08Rik; 4732414G15Rik;
Gene ID : 19106
mRNA Refseq : NM_011163
Protein Refseq : NP_035293
UniProt ID : Q03963
Chromosome Location : 17 49.56 cM; 17 E2
Pathway : Hepatitis C, organism-specific biosystem; Hepatitis C, conserved biosystem; Herpes simplex infection, organism-specific biosystem; Herpes simplex infection, conserved biosystem; Influenza A, organism-specific biosystem; Influenza A, conserved biosystem; Measles, organism-specific biosystem;
Function : ATP binding; RNA binding; double-stranded RNA binding; kinase activity; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; protein tyrosine kinase activity; transferase activity; transferase activity, transferring phosphorus-containing groups;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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How does EIF2AK2 relate to apoptosis? 04/17/2022

EIF2AK2 can be involved in the regulation of apoptosis by triggering the apoptotic process by inducing eIF2α phosphorylation.

Are there other coding variants in the EIF2AK gene? 02/24/2021

Yes, in addition to the primary EIF2AK gene, there are other coding variants that may have different functions and expression patterns.

How is EIF2AK2 related to the development of tumors? 10/18/2020

Studies have shown that EIF2AK2 abnormal expression levels in some tumors may be related to the occurrence and progression of tumors.

What are the possible causes of abnormal EIF2AK2 expression levels? 09/08/2020

Abnormal EIF2AK2 expression levels may be due to genetic mutations, chromosomal abnormalities, environmental factors, etc.

How does EIF2AK2 have to do with viral infection? 05/05/2020

Studies have shown that EIF2AK2 can participate in the regulation of antiviral immune responses and affect the course of viral infections.

What are the applications of EIF2AK2 in drug discovery? 12/28/2019

EIF2AK2 can be used as a target for the development of new drugs, especially in the areas of neurodegenerative diseases and autoimmune diseases.

Customer Reviews (3)

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03/05/2022

    EIF2AK2 has a low immunogenicity and does not cause an abnormal immune response.

    01/02/2022

      Remarkable progress has been made in the application of EIF2AK2 in related fields.

      06/14/2021

        The activity of EIF2AK2 is similar to that of natural proteins and is able to perform its intended biological function.

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