Active Recombinant Mouse Fgfr3 Protein, His & Fc-tagged
Cat.No. : | Fgfr3-836M |
Product Overview : | Recombinant extracellular domain (Met 1-Tyr 367) of mouse FGFR3 (NP_032036.2) precursor was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus. |
- Specification
- Gene Information
- Related Products
Source : | HEK293 |
Species : | Mouse |
Tag : | His & Fc |
Predicted N Terminal : | Glu 21 |
Form : | Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol. |
Bio-activity : | Measured by its ability to bind mouse aFGF in a functional ELISA. |
Molecular Mass : | The recombinant mouse FGFR3/Fc is a disulfide-linked homodimer after removal of the signal peptide. The reduced monomer consists of 595 amino acids and has a predicted molecular mass of 66 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm FGFR3/Fc monomer is approximately 100-110 kDa due to glycosylation. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >92 % as determined by SDS-PAGE. |
Stability : | Samples are stable for up to twelve months from date of receipt at -70ºC. |
Storage : | Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | Fgfr3 fibroblast growth factor receptor 3 [ Mus musculus ] |
Official Symbol : | Fgfr3 |
Synonyms : | FGFR3; fibroblast growth factor receptor 3; heparin-binding growth factor receptor; FR3; Mfr3; sam3; CD333; Flg-2; HBGFR; Fgfr-3; |
Gene ID : | 14184 |
mRNA Refseq : | NM_001163215 |
Protein Refseq : | NP_001156687 |
MIM : | |
UniProt ID : | |
Pathway : | Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; Downstream signaling of activated FGFR, organism-specific biosystem; ESC Pluripotency Pathways, organism-specific biosystem; Endochondral Ossification, organism-specific bio |
Function : | ATP binding; fibroblast growth factor binding; fibroblast growth factor-activated receptor activity; fibroblast growth factor-activated receptor activity; kinase activity; nucleotide binding; protein binding; protein tyrosine kinase activity; receptor act |
Products Types
◆ Recombinant Protein | ||
FGFR3-93H | Recombinant Human FGFR3 Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
Fgfr3-10554M | Recombinant Mouse Fgfr3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Fgfr3-624M | Active Recombinant Mouse Fgfr3 protein(Met1-Tyr367), His-tagged | +Inquiry |
FGFR3-5419H | Recombinant Human Fibroblast Growth Factor Receptor 3, His-tagged | +Inquiry |
FGFR3-001H | Recombinant Human FGFR3 Protein, Fc-His-tagged | +Inquiry |
◆ Lysates | ||
FGFR3-2596MCL | Recombinant Mouse FGFR3 cell lysate | +Inquiry |
FGFR3-001CCL | Recombinant Cynomolgus FGFR3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionFGFR3 testing helps identify specific genetic mutations, allowing for personalized treatment plans tailored to an individual's genetic profile.
FGFR3 testing is becoming more common, especially in cases where specific cancers associated with FGFR3 mutations are suspected.
Yes, FGFR3 status can serve as a prognostic marker, influencing the prediction of disease progression and patient outcomes.
Yes, FGFR3-targeted therapies are being developed for cancer treatment, particularly for patients with FGFR3 mutations.
FGFR3-targeted therapies may involve small molecule inhibitors or monoclonal antibodies that specifically block the activity of mutated FGFR3.
Customer Reviews (3)
Write a reviewResearchers who have utilized FGFR3 protein praise its exceptional performance and reliability in their experiments.
Its high sensitivity enables the identification of low abundance targets, making it highly valuable in immunological research.
Its stability and compatibility with electron microscopy techniques make it an ideal candidate for studying protein structures at high resolution.
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