Active Recombinant Mouse Flt3l protein

• Cat.No.: Flt3l-936M
• Product Overview: Recombinant Mouse Flt3l was expressed in E. coli.

Specification

• Description: FLT3 ligand is a receptor for the fl cytokine has a tyrosine-protein kinase activity & a growth factor that regulates proliferation of early hematopoietic cells. Flt3-Ligand synergizes with other CSFs and interleukins to induce growth and differentiation.
• Source: E. coli
• Species: Mouse
• Form: The FLT3L Mouse protein was lyophilized without any additives.
• Bio-activity: The ED50, calculated by the dose-dependent proliferation of mouse AML5 cells is 1.3-2.0ng/ml.
• Molecular Mass: 18587 Dalton
• Protein length: 163 amino acids
• AA Sequence: MTPDCYFSHS PISSNFKVKF RELTDHLLKD YPVTVAVNLQ DEKHCKALWS LFLAQRWIEQ LKTVAGSKMQ TLLEDVNTEI HFVTSCTFQP LPECLRFVQT NISHLLKDTC TQLLALKPCI GKACQNFSRC LEVQCQPDSS TLLPPRSPIA LEATELPEPR PRQ.
• Purity: Greater than 98.0% as determined by SDS-PAGE.
• Storage: Lyophilized Flt3-Ligand although stable at room temperature for 3 weeks, should be stored desiccated below -18 centigrade. Upon reconstitution Flt-3 Ligand should be stored at 4 centigrade between 2-7 days and for future use below -18 centigrade.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
• Reconstitution: It is recommended to reconstitute the lyophilized Flt3-Ligand in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Gene Information

• Gene Name: Flt3l FMS-like tyrosine kinase 3 ligand [ Mus musculus ]
• Official Symbol: Flt3l
• Synonyms: Ly72L; Flt3lg; flt3 ligand
• Gene ID: 14256
• mRNA Refseq: NM_013520
• Protein Refseq: NP_038548
• UniProt ID: P49772
• Chromosome Location: 7 29.14 cM; 7 B2-C
• Pathway: Cytokine Signaling in Immune system, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Immune System, organism-specific biosystem
• Function: cytokine activity; protein homodimerization activity; receptor tyrosine kinase binding