Recombinant Mouse IgG2aFc protein
Cat.No. : | IgG2aFc-961M |
Product Overview : | Recombinant Mouse IgG2aFc (Glu98-Lys330) protein carried no tag and was expressed in human 293 cells (HEK293). |
- Specification
- Gene Information
- Related Products
Description : | Immunoglobulin G2 (IgG2) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. There are two members of IgG2: IgG2a and IgG2b. It was found that IgG2a was superior to IgG1 in activating complement. The glycosylation of the circulating immunoglobulin-γ (IgG) antibody molecules changes in rheumatoid arthritis. |
Source : | HEK293 |
Species : | Mouse |
Predicted N Terminal : | Glu98 |
Form : | Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 26.4 kDa. As a result of glycosylation, the protein migrates as 25-30 kDa under reducing (R) condition, and 50-60 kDa under non-reducing (NR) condition (SDS-PAGE). |
Protein length : | Glu98-Lys330 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >90% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | IgG2aFc |
Official Symbol : | IgG2aFc |
Synonyms : | Igg2a; Gm16697 |
Gene ID : | 668478 |
UniProt ID : | A0A0A6YW37 |
Products Types
◆ Recombinant Protein | ||
IgG2aFc-1369M | Recombinant Mouse IgG2aFc protein(Glu98-Lys330), Biotinylated | +Inquiry |
IgG2aFc-0213M | Active Recombinant Mouse IgG2aFc protein, Avi-tagged, Biotinylated | +Inquiry |
IgG2aFc-11M | Recombinant Mouse IgG2a Fc protein | +Inquiry |
IgG2aFc-961MB | Recombinant Mouse IgG2aFc protein, Biotinylated | +Inquiry |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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