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Recombinant Mouse Lair1 protein, His-tagged

Cat.No. : Lair1-33M
Product Overview : Recombinant mouse Lair1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
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  • Gene Information
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Description : Lair1, as known as leukocyte-associated immunoglobulin-like receptor 1 isoform a, is an inhibitory receptor of the lg superfamily that is related to inhibitory members of KIR and ILT/CD85 families. This protein is well expressed NK cells, T cells, B cells, monocytes, macrophages, immature neutrophils, dendritic cells and most thymocytes. Also, it functions as an inhibitory receptor not only on NK cells, but on human T cells.
Source : Insect cells
Species : Mouse
Tag : His
Form : Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
Molecular Mass : 15.0kDa (132aa)
18-28kDa (SDS-PAGE under reducing conditions.)
AA Sequence : ADPQEGSLPD ITIFPNSSLM ISQGTFVTVV CSYSDKHDLY NMVRLEKDGS TFMEKSTEPY KTEDEFEIGP VNETITGHYS CIYSKGITWS ERSKTLELKV IKENVIQTPA PGPTSDTSWL KTYSIYHHHH HH
Endotoxin : < 1.0 EU per 1 microgram of protein (determined by LAL method)
Purity : > 90% by SDS - PAGE
Storage : Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20centigrade or -70centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 0.5mg/ml (determined by Absorbance at 280nm)
Gene Name : Lair1 leukocyte-associated Ig-like receptor 1 [ Mus musculus ]
Official Symbol : Lair1
Synonyms : LAIR1; mLAIR1; Lair-1; mLair-1; BB115266
Gene ID : 52855
mRNA Refseq : NM_001113474
Protein Refseq : NP_001106945
Function : receptor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How can LAIR1 impact the field of regenerative medicine? 07/12/2021

LAIR1's role in immune regulation may have implications for reducing immune rejection in regenerative medicine and tissue engineering.

Are there any ongoing clinical trials involving LAIR1 protein? 09/24/2020

Some clinical trials are exploring the therapeutic potential of targeting LAIR1 in cancer immunotherapy and autoimmune disease management.

How can LAIR1 protein impact immunotherapy approaches? 01/26/2020

LAIR1 can be targeted to enhance the effectiveness of immunotherapy, as inhibiting LAIR1 may boost the immune system's response against cancer cells.

Is LAIR1 protein involved in inflammatory conditions? 02/02/2017

Yes, LAIR1's role in immune modulation makes it relevant in inflammatory conditions. Targeting LAIR1 may be a strategy to manage inflammation.

Are there any drugs or biologics targeting LAIR1 in development? 01/16/2016

There are experimental drugs and biologics that target LAIR1 currently in preclinical and early clinical development.

Customer Reviews (3)

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Reviews
09/06/2021

    Another advantage of using LAIR1 protein in trials is its potential as a therapeutic agent.

    01/03/2020

      The manufacturer's support and expertise further enhance the utility of LAIR1 in my experimental work, ensuring reliable and high-quality results.

      01/27/2017

        This collaborative partnership greatly contributes to the success of my research projects and facilitates meaningful contributions to the scientific community.

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