Recombinant Mouse Lair1 protein, His-tagged
Cat.No. : | Lair1-33M |
Product Overview : | Recombinant mouse Lair1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | Lair1, as known as leukocyte-associated immunoglobulin-like receptor 1 isoform a, is an inhibitory receptor of the lg superfamily that is related to inhibitory members of KIR and ILT/CD85 families. This protein is well expressed NK cells, T cells, B cells, monocytes, macrophages, immature neutrophils, dendritic cells and most thymocytes. Also, it functions as an inhibitory receptor not only on NK cells, but on human T cells. |
Source : | Insect cells |
Species : | Mouse |
Tag : | His |
Form : | Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
Molecular Mass : | 15.0kDa (132aa) 18-28kDa (SDS-PAGE under reducing conditions.) |
AA Sequence : | ADPQEGSLPD ITIFPNSSLM ISQGTFVTVV CSYSDKHDLY NMVRLEKDGS TFMEKSTEPY KTEDEFEIGP VNETITGHYS CIYSKGITWS ERSKTLELKV IKENVIQTPA PGPTSDTSWL KTYSIYHHHH HH |
Endotoxin : | < 1.0 EU per 1 microgram of protein (determined by LAL method) |
Purity : | > 90% by SDS - PAGE |
Storage : | Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20centigrade or -70centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5mg/ml (determined by Absorbance at 280nm) |
Gene Name : | Lair1 leukocyte-associated Ig-like receptor 1 [ Mus musculus ] |
Official Symbol : | Lair1 |
Synonyms : | LAIR1; mLAIR1; Lair-1; mLair-1; BB115266 |
Gene ID : | 52855 |
mRNA Refseq : | NM_001113474 |
Protein Refseq : | NP_001106945 |
Function : | receptor activity; |
Products Types
◆ Recombinant Protein | ||
LAIR1-3001R | Recombinant Rat LAIR1 Protein, His (Fc)-Avi-tagged | +Inquiry |
LAIR1-166H | Recombinant Human LAIR1 Protein, MYC/DDK-tagged | +Inquiry |
LAIR1-092H | Recombinant Human LAIR1 Protein, C-His-tagged | +Inquiry |
Lair1-1728M | Recombinant Mouse Lair1 Protein, His-tagged | +Inquiry |
LAIR1-091H | Recombinant Human LAIR1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
LAIR1-1331MCL | Recombinant Mouse LAIR1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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- Q&As
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Q&As (5)
Ask a questionLAIR1's role in immune regulation may have implications for reducing immune rejection in regenerative medicine and tissue engineering.
Some clinical trials are exploring the therapeutic potential of targeting LAIR1 in cancer immunotherapy and autoimmune disease management.
LAIR1 can be targeted to enhance the effectiveness of immunotherapy, as inhibiting LAIR1 may boost the immune system's response against cancer cells.
Yes, LAIR1's role in immune modulation makes it relevant in inflammatory conditions. Targeting LAIR1 may be a strategy to manage inflammation.
There are experimental drugs and biologics that target LAIR1 currently in preclinical and early clinical development.
Customer Reviews (3)
Write a reviewAnother advantage of using LAIR1 protein in trials is its potential as a therapeutic agent.
The manufacturer's support and expertise further enhance the utility of LAIR1 in my experimental work, ensuring reliable and high-quality results.
This collaborative partnership greatly contributes to the success of my research projects and facilitates meaningful contributions to the scientific community.
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