Recombinant Mouse PTEN Protein
Cat.No. : | PTEN-13631M |
Product Overview : | Recombinant Mouse PTEN full length or partial length protein was expressed. |
- Specification
- Gene Information
- Related Products
Source : | Mammalian Cells |
Species : | Mouse |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC. |
Storage Buffer : | PBS buffer |
Gene Name : | Pten phosphatase and tensin homolog [ Mus musculus ] |
Official Symbol : | PTEN |
Gene ID : | 19211 |
mRNA Refseq : | NM_008960.2 |
Protein Refseq : | NP_032986.1 |
MIM : | |
UniProt ID : | O08586 |
Products Types
◆ Recombinant Protein | ||
PTEN-31H | Recombinant Human PTEN Protein, His-tagged | +Inquiry |
Pten-1996M | Recombinant Mouse Pten Protein, His-tagged | +Inquiry |
PTEN-3504R | Recombinant Rhesus Macaque PTEN Protein, His (Fc)-Avi-tagged | +Inquiry |
PTEN-342H | Recombinant Human PTEN Protein, His-tagged | +Inquiry |
PTEN-7249M | Recombinant Mouse PTEN Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PTEN-2721HCL | Recombinant Human PTEN 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionIn addition to its lipid phosphatase activity, PTEN has an additional function known as a scaffolding protein that contributes to its tumor-suppressive role.
PTEN primarily exerts its lipid phosphatase function in the cytoplasm, where it regulates the PI3K/AKT pathway.
The significance of FBXO22-mediated degradation of nuclear PTEN in promoting tumorigenesis involves the loss of PTEN's tumor-suppressive functions, leading to uncontrolled cell growth.
The expression of nuclear PTEN (核PTEN) is regulated, especially in the context of tumorigenesis, through mechanisms involving post-translational modifications and subcellular localization.
Differences in expression patterns of nuclear PTEN and cytoplasmic PTEN in various cancer processes include alterations in nuclear PTEN levels contributing to tumorigenesis.
The classical function of the PTEN protein is to regulate cell growth and prevent tumor formation by suppressing the PI3K/AKT signaling pathway.
Nuclear PTEN plays a role in mediating the non-phosphatase-dependent function related to genomic stability and DNA repair.
Customer Reviews (3)
Write a reviewGel electrophoresis consistently displayed well-defined bands, affirming the product's purity and reliability.
The insights gained from the product's application justified its cost, marking a prudent investment in our research endeavors.
Comprehensive documentation streamlined the integration of the product into our experimental workflow.
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