Active Recombinant Mouse Prdx1 Protein, His-tagged

• Cat.No.: Prdx1-60M
• Product Overview: Recombinant mouse Prdx1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Specification

• Description: Prdx1, also known as peroxiredoxin-1, is an important member of peroxiredoxins (Prdxs) regulating various cellular signaling and differentiation. It confers an aggressive survival phenotype of cancer cells and drug-resistance. This protein is also identified as a red blood cell factor which enhances natural killer (NK) cell activity.
• Source: Insect cells
• Species: Mouse
• Tag: His tag
• Form: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
• Bio-activity: Specific activity is >2,500 pmol/min/ug. Enzymatic activity is defined as the amount of hydroperoxide that 1ug of enzyme can reduce at 25°C for minute.
• Molecular Mass: 23.2kDa (207aa)18-28KDa (SDS–PAGE under reducing conditions.)
• AA Sequence: MSSGNAKIGY PAPNFKATAV MPDGQFKDIS LSEYKGKYVV FFFYPLDFTF VCPTEIIAFS DRADEFKKLN CQVIGASVDS HFCHLAWINTPKKQGGLGPM NIPLISDPKR TIAQDYGVLK ADEGISFRGL FIIDDKGILR QITINDLPVG RSVDEIIRLV QAFQFTDKHG EVCPAGWKPGSDTIKPDVNK SKEYFSKQKL EHHHHHH
• Endotoxin: < 1.0 EU per 1 microgram of protein (determined by LAL method)
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20Centigrade or -70Centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5mg/ml (determined by Absorbance at 280nm)

Gene Information

• Gene Name: Prdx1 peroxiredoxin 1 [ Mus musculus ]
• Official Symbol: Prdx1
• Synonyms: PRDX1; PAG; OSF3; Paga; PrxI; TDX2; TPxA; prx1; MSP23
• Gene ID: 18477
• mRNA Refseq: NM_011034
• Protein Refseq: NP_035164
• Pathway: Peroxisome, organism-specific biosystem; Peroxisome, conserved biosystem; phosphate acquisition II, organism-specific biosystem
• Function: antioxidant activity; heme binding; oxidoreductase activity; peroxidase activity; peroxiredoxin activity; protein homodimerization activity; thioredoxin peroxidase activity