Recombinant Mouse Scarb1 Protein, His & Fc-tagged

• Cat.No.: Scarb1-859M
• Product Overview: Recombinant mature form of mouse SRB1 (NP_058021.1) extracellular domain (Pro 33-Val 440) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.

Specification

• Source: HEK293
• Species: Mouse
• Tag: His & Fc
• Predicted N Terminal: Pro 33
• Form: Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol.
• Molecular Mass: The secreted recombinant mouse SRB1/Fc is a disulfide-linked homodimer The reduced monomer comprises 656 amino acids with a predicted molecular mass of 74 kDa. As a result of glycosylation, it migrates as an approximately 115-120 kDa band in SDS-PAGE under reducing conditions.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >95 % as determined by SDS-PAGE.
• Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
• Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: Scarb1 scavenger receptor class B, member 1 [ Mus musculus ]
• Official Symbol: Scarb1
• Synonyms: CD36; Cla1; SRBI; Srb1; Cla-1; Hdlq1; SR-B1; SR-BI; Cd36l1; Chohd1; Hlb398; mSR-BI; AI120173; D5Ertd460e; HDL QTL 1; scavenger receptor class B type I; scavenger receptor class B1
• Gene ID: 20778
• mRNA Refseq: NM_001205082
• Protein Refseq: NP_001192011
• UniProt ID: Q61009
• Chromosome Location: 5 64.11 cM; 5 G1.1
• Pathway: Aldosterone synthesis and secretion, organism-specific biosystem; Bile secretion, organism-specific biosystemFat digestion and absorption, organism-specific biosystem
• Function: apolipoprotein A-I binding; apolipoprotein binding; high-density lipoprotein particle receptor activity