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Recombinant Mouse TOP2B Protein

Cat.No. : TOP2B-17231M
Product Overview : Recombinant Mouse TOP2B full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Mouse
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Storage Buffer : PBS buffer
Gene Name : Top2b topoisomerase (DNA) II beta [ Mus musculus ]
Official Symbol : TOP2B
Gene ID : 21974
mRNA Refseq : NM_009409.2
Protein Refseq : NP_033435.2
MIM :
UniProt ID : Q64511

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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What cellular processes does TOP2B participate in, besides replication? 01/14/2022

TOP2B is crucial for chromosome segregation, transcription, and DNA recombination, playing a central role in maintaining genomic stability.

How does TOP2B contribute to the regulation of chromatin structure? 06/18/2021

TOP2B helps in remodeling chromatin by resolving supercoils, influencing the accessibility of DNA for various cellular processes.

What is the relationship between TOP2B and drug resistance in cancer treatment? 04/07/2020

Increased expression of TOP2B has been associated with resistance to certain chemotherapeutic agents, impacting the efficacy of cancer treatments.

What is the consequence of TOP2B mutations on cellular function? 08/22/2019

Mutations in TOP2B can lead to impaired DNA repair, genomic instability, and increased susceptibility to various diseases, including certain types of cancer.

How is TOP2B expression regulated in cells? 11/03/2018

Various factors, including cell cycle progression and response to DNA damage, influence the expression of TOP2B to meet the dynamic needs of the cell.

Customer Reviews (3)

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Reviews
01/08/2022

    The quality of this product exceeded my expectations, providing precise and reliable results in our experiments.

    09/25/2019

      Rapid delivery! Ordered and received the product within a short timeframe, allowing us to proceed with our experiments without delays.

      04/18/2018

        Exceptional service!

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