Recombinant Mouse Tnfrsf11b Protein, His-tagged

Cat.No.: Tnfrsf11b-70M
Product Overview: Recombinant mouse Tnfrsf11B, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Description: Tnfrsf11b, also known as tumor necrosis factor receptor superfamily member 11B, is a member of the tumor necrosis factor receptor TNFR superfamily. It inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Also It plays a role in preventing arterial calcification.
Source: Insect cells
Species: Mouse
Tag: His tag
Form: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
Molecular Mass: 44.4kDa (388aa)40-57kDa (SDS-PAGE under reducing conditions)
AA Sequence: ETLPPKYLHY DPETGHQLLC DKCAPGTYLK QHCTVRRKTL CVPCPDHSYT DSWHTSDECV YCSPVCKELQ SVKQECNRTH NRVCECEEGRYLEIEFCLKH RSCPPGSGVV QAGTPERNTV CKKCPDGFFS GETSSKAPCI KHTNCSTFGL LLIQKGNATH DNVCSGNREA TQKCGIDVTLCEEAFFRFAV PTKIIPNWLS VLVDSLPGTK VNAESVERIK RRHSSQEQTF QLLKLWKHQN RDQEMVKKII QDIDLCESSV QRHLGHSNLTTEQLLALMES LPGKKISPEE IERTRKTCKS SEQLLKLLSL WRIKNGDQDT LKGLMYALKH LKTSHFPKTV THSLRKTMRF LHSFTMYRLYQKLFLEMIGN QVQSVKISCL LEHHHHHH
Endotoxin: < 1.0 EU per 1 microgram of protein (determined by LAL method)
Purity: >90% by SDS - PAGE
Storage: Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20Centigrade or -70Centigrade. Avoid repeated freezing and thawing cycles.
Concentration: 0.25mg/ml (determined by Absorbance at 280nm)
Gene Name: Tnfrsf11b tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) [ Mus musculus ]
Official Symbol: Tnfrsf11b
Synonyms: TNFRSF11B; osteoprotegerin; Opg; TR1; OCIF
Gene ID: 18383
mRNA Refseq: NM_008764
Protein Refseq: NP_032790
MIM:
UniProt ID:
Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Osteoblast, organism-specific biosystem; Osteoclast, organism-specific biosystem; Osteoclast differentiation, organism-specific biosystem; Osteoclast differentiation, conserved biosystem;
Function: binding; receptor activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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