Recombinant Rat ADRA2C Protein
Cat.No. : | ADRA2C-543R |
Product Overview : | Recombinant Rat ADRA2C full length or partial length protein was expressed. |
- Specification
- Gene Information
- Related Products
Source : | Mammalian Cells |
Species : | Rat |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC. |
Storage Buffer : | PBS buffer |
Gene Name : | Adra2c adrenoceptor alpha 2C [ Rattus norvegicus ] |
Official Symbol : | ADRA2C |
Gene ID : | 24175 |
mRNA Refseq : | NM_138506.1 |
Protein Refseq : | NP_612515.1 |
MIM : | |
UniProt ID : | P22086 |
Products Types
◆ Recombinant Protein | ||
ADRA2C-199R | Recombinant Rat ADRA2C Protein, His (Fc)-Avi-tagged | +Inquiry |
ADRA2C-364M | Recombinant Mouse ADRA2C Protein, His (Fc)-Avi-tagged | +Inquiry |
Adra2c-3334R | Recombinant Rat Adra2c, His-tagged | +Inquiry |
ADRA2C-1384M | Recombinant Mouse ADRA2C Protein | +Inquiry |
ADRA2C-11834Z | Recombinant Zebrafish ADRA2C | +Inquiry |
◆ Lysates | ||
ADRA2C-8999HCL | Recombinant Human ADRA2C 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-2182 | cAMP ADRA2C CHO-K1 GPCR Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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- Q&As
- Reviews
Q&As (18)
Ask a questionGenetic variations in the ADRA2C gene can affect the function of ADRA2C receptors and contribute to the development of various medical conditions. Identifying these variations can help clinicians develop more personalized treatments for patients with these conditions, and may also improve our understanding of the underlying mechanisms involved in adrenergic signaling.
Yes, ADRA2C dysfunction can affect children and adolescents, particularly in the case of ADHD. However, children and adolescents may require different treatment strategies than adults. It is important for healthcare providers to carefully evaluate and monitor children and adolescents with ADRA2C dysfunction to ensure proper management and appropriate medication dosing.
ADRA2C-targeted treatments may be used in combination with other therapies to improve patient outcomes. For example, they could be used alongside traditional antidepressant medications to improve treatment response in patients with depression. In patients with hypertension, ADRA2C-targeted treatments may be used in combination with other antihypertensive drugs to achieve better blood pressure control.
Yes, ongoing research continues to explore the role of ADRA2C in the development and progression of medical conditions such as hypertension, depression, and ADHD. Additionally, researchers are exploring the potential use of ADRA2C-targeted medications for the treatment of these conditions, and the development of more targeted and effective therapies is ongoing.
ADRA2C proteins are a subtype of adrenergic receptors found in various tissues throughout the body. These receptors play a crucial role in regulating the activity of the sympathetic nervous system, which controls many vital bodily processes, including the regulation of blood pressure and heart rate.
There are several different approaches to targeting ADRA2C proteins for medical treatments, including the development of drugs that can selectively bind to and activate or inhibit these receptors. These drugs can be used to regulate the activity of the sympathetic nervous system and potentially treat a range of conditions associated with dysregulation of adrenergic signaling.
While some cases of ADRA2C dysfunction may be due to inherited genetic variations or medical conditions that cannot be prevented, certain lifestyle choices may help reduce the risk of adrenergic dysfunction. For example, maintaining a healthy diet, getting regular exercise, reducing stress, and avoiding tobacco and excessive alcohol consumption may help regulate ADRA2C function and prevent related medical conditions such as hypertension and depression.
ADRA2C dysfunction can be evaluated and diagnosed through various physiological and psychiatric tests and assessments, including blood pressure monitoring, electrocardiogram (ECG) tests, attention tests, and psychological evaluations. Genetic testing may also be performed to identify any genetic variations that may impact ADRA2C function.
Developing ADRA2C-targeted treatments presents several challenges. For example, it can be difficult to develop drugs that selectively target ADRA2C without affecting other adrenergic receptors. Additionally, genetic variations that influence ADRA2C function can make it difficult to predict patient response to treatments. Finally, the complex interactions between the adrenergic system and other physiological systems pose a challenge when trying to develop effective treatments.
ADRA2C proteins differ from other types of adrenergic receptors in terms of their structure, function, and distribution throughout the body. Unlike other adrenergic receptors, ADRA2C proteins primarily bind to the neurotransmitter norepinephrine, and they are found in a relatively small number of tissues.
While there is limited research on natural supplements or herbs specifically targeting ADRA2C function, some natural remedies may have indirect effects on the adrenergic system. For example, certain herbal remedies such as ashwagandha, ginseng, and rhodiola have been shown to reduce stress and improve mood, potentially impacting the adrenergic system. However, it is important to discuss the use of natural supplements with a healthcare provider to ensure they are safe and appropriate for individual use.
Like all medications, ADRA2C-targeted treatments can have side effects. Some of the potential side effects associated with these treatments include changes in heart rate and blood pressure, sleep disturbances, gastrointestinal issues, and changes in mood or behavior. The specific side effects will depend on the type of treatment and the individual patient.
Like any medication, there is the potential for side effects with ADRA2C-targeted treatments. Common side effects may include dizziness, headaches, constipation, and dry mouth. Some patients may also experience changes in heart rate or blood pressure, particularly if they are taking other medications that impact the adrenergic system.
While medication is often necessary for patients with adrenergic dysfunction, there are also lifestyle changes that can help regulate ADRA2C function and improve overall health. For example, maintaining a healthy diet, getting regular exercise, reducing stress, and avoiding tobacco and excessive alcohol consumption may all have a positive impact on the adrenergic system. Additionally, regular sleep patterns and good sleep hygiene may improve overall adrenergic regulation.
ADRA2C dysfunction has been linked to several mental health conditions, including depression, anxiety, and attention-deficit/hyperactivity disorder (ADHD). Research suggests that alterations in adrenergic function, including changes in ADRA2C levels and activity, may play a role in the development and progression of these conditions. Targeting ADRA2C with medication may therefore be a promising treatment approach for individuals with these conditions.
Many researchers are currently studying ADRA2C proteins and their potential role in various medical conditions. Some studies are focused on developing new drugs that can selectively target and regulate ADRA2C function, while others are exploring the genetic and environmental factors that influence ADRA2C regulation and function.
Adrenergic dysfunction has been associated with several medical conditions, including hypertension, anxiety disorders, depression, and attention deficit hyperactivity disorder (ADHD). The precise role that ADRA2C proteins play in these conditions can vary, and more research is needed to fully understand their function.
Lifestyle changes, such as regular exercise, stress reduction techniques, and a healthy diet, may help regulate ADRA2C function by reducing stress and promoting overall physical and mental health. Natural remedies, such as herbal supplements, may also be beneficial in some cases. However, more research is needed to fully understand the effects of these practices on ADRA2C function.
Customer Reviews (5)
Write a reviewThe manufacturer's technical support team is incredibly efficient and capable of addressing any concerns or issues that may arise during the process.
The manufacturer has also demonstrated a keen understanding of my needs and has gone above and beyond to provide me with excellent technical support, which has proven to be invaluable in helping me navigate any potential obstacles that may arise.
Based on my analysis, I can confidently affirm that the protein in question exhibits a remarkable level of quality that makes it ideal for fulfilling the requirements of my experiments.
I am confident that utilizing this protein will enable me to achieve precise and consistent results and meet my research objectives effectively.
the level of consistency and purity exhibited by the protein is truly exceptional, providing me with the confidence that my experiments will yield results that are both accurate and reliable.
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