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Recombinant Rat AQP9 Protein

Cat.No. : AQP9-742R
Product Overview : Recombinant Rat AQP9 full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Rat
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Storage Buffer : PBS buffer
Gene Name : Aqp9 aquaporin 9 [ Rattus norvegicus ]
Official Symbol : AQP9
Gene ID : 65054
mRNA Refseq : NM_022960.2
Protein Refseq : NP_075249.1
MIM :
UniProt ID : P56627

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (30)

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Are there any diseases or conditions associated with AQP9 dysregulation? 04/10/2023

Yes, dysregulation of AQP9 has been implicated in various pathologies. For example, altered expression or function of AQP9 has been associated with liver diseases, such as non-alcoholic fatty liver disease and liver cancer. Additionally, AQP9 dysregulation may also contribute to conditions like obesity and diabetes.

Are there any known genetic mutations or polymorphisms in the AQP9 gene? 01/08/2023

Yes, several genetic mutations and polymorphisms have been identified in the AQP9 gene. These variations in the gene sequence can lead to altered expression or function of AQP9 and may be associated with certain diseases or conditions. However, the specific impact of these genetic variations on AQP9 function and their clinical significance is still being investigated.

Are there any known genetic mutations or polymorphisms in the AQP9 gene? 01/08/2023

Yes, several genetic mutations and polymorphisms have been identified in the AQP9 gene. These variations in the gene sequence can lead to altered expression or function of AQP9 and may be associated with certain diseases or conditions. However, the specific impact of these genetic variations on AQP9 function and their clinical significance is still being investigated.

In which tissues or organs is AQP9 primarily expressed? 08/03/2022

AQP9 is primarily expressed in tissues and organs involved in metabolism, such as the liver, adipose tissue, kidney, and intestine.

Are there any known AQP9 inhibitors or activators? 02/26/2022

Currently, there are no specific inhibitors or activators that exclusively target AQP9. However, certain compounds, such as mercury chloride, have been reported to inhibit AQP9 activity, although they may also affect other aquaporins.

Is AQP9 involved in the transport of water and solutes across the blood-brain barrier? 10/04/2021

While AQP9 is not highly expressed in the blood-brain barrier, it has been detected in certain brain regions. Its role in water and solute transport in the brain is not completely understood, but studies suggest that AQP9 may play a role in maintaining brain osmotic balance and energy metabolism.

Does AQP9 play a role in the immune system? 09/24/2021

Yes, AQP9 has been implicated in immune cell function. It is expressed in lymphoid tissues, such as the spleen and lymph nodes, and may contribute to immune cell migration and activation by facilitating the transport of small molecules required for immune responses.

Can alterations in AQP9 expression or function influence drug transport? 09/14/2021

Yes, AQP9 has been implicated in influencing the transport of certain drugs. Its expression in the liver, intestine, and kidney suggests that it may play a role in drug absorption, distribution, and excretion. Modulating AQP9 activity could potentially impact drug efficacy and toxicity.

Is AQP9 present in all tissues and organs? 03/25/2021

No, AQP9 is not present in all tissues and organs. Its expression is primarily found in tissues involved in metabolic processes, such as the liver, kidney, adipose tissue, and gastrointestinal tract. AQP9 expression may vary between different cell types within a tissue, reflecting their specific roles and metabolic functions.

Is AQP9 present in all tissues and organs? 03/25/2021

No, AQP9 is not present in all tissues and organs. Its expression is primarily found in tissues involved in metabolic processes, such as the liver, kidney, adipose tissue, and gastrointestinal tract. AQP9 expression may vary between different cell types within a tissue, reflecting their specific roles and metabolic functions.

Are there any known AQP9 inhibitors? 12/11/2020

Several compounds have been identified as potential inhibitors of AQP9. For example, phloretin and its derivatives have been shown to inhibit AQP9-mediated glycerol transport. However, further research is needed to develop more specific and effective inhibitors that can selectively target AQP9 without interfering with other aquaporin proteins or essential physiological functions.

Can AQP9 expression be regulated by environmental factors or external stimuli? 08/15/2020

Yes, AQP9 expression can be modulated by various environmental factors and external stimuli. For example, changes in osmolarity, cytokines, hormones, and certain drugs can influence AQP9 expression levels. These regulatory mechanisms allow cells to adapt to different physiological conditions and respond to external signals.

Can AQP9 expression be regulated by environmental factors or external stimuli? 08/15/2020

Yes, AQP9 expression can be modulated by various environmental factors and external stimuli. For example, changes in osmolarity, cytokines, hormones, and certain drugs can influence AQP9 expression levels. These regulatory mechanisms allow cells to adapt to different physiological conditions and respond to external signals.

What other aquaporin proteins are closely related to AQP9? 04/09/2020

AQP9 belongs to a subfamily of aquaporin proteins known as the aquaglyceroporins. Other aquaglyceroporins include AQP3, AQP7, and AQP10, which also facilitate the transport of water and small solutes like glycerol and urea.

What other aquaporin proteins are closely related to AQP9? 04/09/2020

AQP9 belongs to a subfamily of aquaporin proteins known as the aquaglyceroporins. Other aquaglyceroporins include AQP3, AQP7, and AQP10, which also facilitate the transport of water and small solutes like glycerol and urea.

Are there any genetic variations or mutations associated with AQP9? 07/22/2019

Yes, several genetic variations and mutations in the AQP9 gene have been identified. Some of these variations have been associated with altered glycerol and water transport, and are linked to conditions such as obesity and metabolic syndrome.

Are there any diseases or conditions specifically linked to AQP9 dysregulation? 12/18/2018

Dysregulation of AQP9 has been implicated in various diseases and conditions. For example, altered AQP9 expression has been observed in obesity, type 2 diabetes, liver cirrhosis, and certain kidney disorders. Additionally, AQP9 has been associated with tumor growth and progression in certain types of cancer.

Are there any diseases or conditions specifically linked to AQP9 dysregulation? 12/18/2018

Dysregulation of AQP9 has been implicated in various diseases and conditions. For example, altered AQP9 expression has been observed in obesity, type 2 diabetes, liver cirrhosis, and certain kidney disorders. Additionally, AQP9 has been associated with tumor growth and progression in certain types of cancer.

Are there any ongoing studies or clinical trials related to AQP9? 09/03/2018

While there are limited clinical trials specifically targeting AQP9, ongoing research is exploring its role in various diseases. Studies are investigating the association between AQP9 polymorphisms and metabolic disorders, as well as the potential therapeutic implications of modulating AQP9 function in liver diseases and other conditions.

Are there any ongoing studies or clinical trials related to AQP9? 09/03/2018

While there are limited clinical trials specifically targeting AQP9, ongoing research is exploring its role in various diseases. Studies are investigating the association between AQP9 polymorphisms and metabolic disorders, as well as the potential therapeutic implications of modulating AQP9 function in liver diseases and other conditions.

Can AQP9 be targeted using drugs or therapies? 05/03/2018

Modulating AQP9 function or expression using drugs or therapies is an area of ongoing research. While specific drugs targeting AQP9 are not currently available, compounds that influence AQP9 activity or expression indirectly, such as hormones or cytokines, may have therapeutic potential.

Can AQP9 be targeted using drugs or therapies? 05/03/2018

Modulating AQP9 function or expression using drugs or therapies is an area of ongoing research. While specific drugs targeting AQP9 are not currently available, compounds that influence AQP9 activity or expression indirectly, such as hormones or cytokines, may have therapeutic potential.

Can modulating AQP9 function have therapeutic potential? 03/25/2018

Modulating AQP9 function holds potential therapeutic value, particularly in conditions where glycerol and metabolite transport is dysregulated, such as liver diseases and metabolic disorders. However, further research is needed to understand the complex roles of AQP9 and develop suitable strategies for therapeutic interventions.

Can AQP9 play a role in the development of drug resistance in cancer? 10/03/2017

There is accumulating evidence suggesting that AQP9 may contribute to drug resistance in various types of cancer. Studies have shown that AQP9 expression can enhance the efflux of anticancer drugs from cancer cells, reducing their effectiveness. Targeting AQP9-mediated drug efflux is being explored as a potential strategy to overcome drug resistance in cancer therapy.

Can AQP9 play a role in the development of drug resistance in cancer? 10/03/2017

There is accumulating evidence suggesting that AQP9 may contribute to drug resistance in various types of cancer. Studies have shown that AQP9 expression can enhance the efflux of anticancer drugs from cancer cells, reducing their effectiveness. Targeting AQP9-mediated drug efflux is being explored as a potential strategy to overcome drug resistance in cancer therapy.

Is AQP9 involved in the transport of other solutes apart from water and glycerol? 04/25/2017

Yes, in addition to water and glycerol, AQP9 also facilitates the transport of other solutes, including urea and various metabolites. This versatile transport capacity makes AQP9 important in maintaining overall cellular homeostasis.

Is AQP9 involved in the transport of other solutes besides glycerol? 11/24/2016

Yes, in addition to glycerol, AQP9 is capable of transporting other solutes, including urea and monocarboxylates like lactate and pyruvate. The relative contribution of these solutes to AQP9-mediated transport may vary depending on the tissue and physiological conditions.

Is AQP9 involved in the transport of other solutes besides glycerol? 11/24/2016

Yes, in addition to glycerol, AQP9 is capable of transporting other solutes, including urea and monocarboxylates like lactate and pyruvate. The relative contribution of these solutes to AQP9-mediated transport may vary depending on the tissue and physiological conditions.

Can dysregulation of AQP9 be a potential therapeutic target for liver diseases? 07/12/2016

Yes, given the involvement of AQP9 in glycerol metabolism and the liver's role in lipid and glucose metabolism, modulating AQP9 function has been proposed as a potential therapeutic strategy for liver diseases. However, further research is needed to fully understand the mechanisms and potential benefits of targeting AQP9 in liver disorders.

Can dysregulation of AQP9 be a potential therapeutic target for liver diseases? 07/12/2016

Yes, given the involvement of AQP9 in glycerol metabolism and the liver's role in lipid and glucose metabolism, modulating AQP9 function has been proposed as a potential therapeutic strategy for liver diseases. However, further research is needed to fully understand the mechanisms and potential benefits of targeting AQP9 in liver disorders.

Customer Reviews (8)

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Reviews
02/12/2019

    It has become an indispensable tool in my experiments, consistently meeting my needs and providing valuable insights.

    10/03/2018

      Its purity and consistency guarantee reliable and reproducible results, ensuring the reliability of my research outcomes.

      09/09/2018

        One of the standout features of the AQP9 protein is the excellent technical support provided by the manufacturer.

        12/13/2017

          the AQP9 protein demonstrates outstanding performance in various experimental applications.

          05/19/2017

            In addition to its high-quality standards, the manufacturer of AQP9 protein offers excellent technical support.

            01/09/2017

              The AQP9 protein stands out for its exceptional quality, making it an excellent choice to meet my experimental requirements.

              07/15/2016

                the ease of use and compatibility of the AQP9 protein with various techniques further enhances its appeal.

                05/12/2016

                  The AQP9 protein is a top-quality product that is sure to fulfill my experimental requirements.

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