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Recombinant Rat AVPR2 Protein

Cat.No. : AVPR2-908R
Product Overview : Recombinant Rat AVPR2 full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Rat
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Storage Buffer : PBS buffer
Gene Name : Avpr2 arginine vasopressin receptor 2 [ Rattus norvegicus ]
Official Symbol : AVPR2
Gene ID : 25108
mRNA Refseq : NM_019136.1
Protein Refseq : NP_062009.1
MIM :
UniProt ID : Q00788

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the role of AVPR2 protein in urine concentration? 04/27/2022

This protein promotes the production of cAMP in renal tubular epithelial cells by activating adenylyl cyclase-adenylyase system, thereby increasing the expression and transport of aquaporin-2 and increasing urine concentration.

What signal transduction pathways do AVPR2 proteins associate with? 09/07/2021

The protein is associated with signal transduction pathways related to adenylyl cyclase-adenylyl enzyme system and increases intracellular cAMP levels by activating adenylyl cyclase.

Which diseases are associated with AVPR2 protein mutations? 05/24/2021

Mutations in the AVPR2 protein are associated with nephrogenic diabetes insipidus, a disorder in which renal tubules are insensitive to arginine vasopressin, resulting in a failure to concentrate urine.

In which tissues is AVPR2 protein expressed? 08/22/2020

It is mainly expressed in renal tubules, especially at the apices of collecting duct cells.

What are the prospects of AVPR2 protein in drug development? 06/05/2020

Because of its involvement in the regulation of urine concentration and dilution, AVPR2 protein is considered a potential target for drug development. Researchers are exploring the development of drugs that interact with AVPR2 protein for the treatment of related diseases

Which hormone does AVPR2 protein bind to? 02/13/2019

AVPR2 protein binds to the antidiuretic hormone arginine vasopressin and, through its binding to arginine vasopressin, triggers the activation of intracellular signal transduction pathways.

Customer Reviews (3)

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Reviews
09/05/2022

    Beacuse preparation cost is very low and the cost performance is very high.

    09/26/2019

      The activity retention time is very long and the activity can be maintained for a long time.

      03/23/2019

        This labeling effect is very good, and fluorescent labeling can be performed, etc.

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