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Recombinant Rat Chi3l1 protein, His-tagged

Cat.No. : Chi3l1-1375R
Product Overview : Recombinant Rat Chi3l1(Tyr117~Lys364) fused with His tag at N-terminal was expressed in E. coli.
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Description : Chi3l1 played an important role in many functions.
Source : E. coli
Species : Rat
Tag : His
Form : PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300
Molecular Mass : 31.0kD
Protein length : Tyr117~Lys364
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : > 95%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution : Reconstitute in PBS or others.
Gene Name : Chi3l1 chitinase 3-like 1 (cartilage glycoprotein-39) [ Rattus norvegicus ]
Official Symbol : Chi3l1
Synonyms : CHI3L1; chitinase 3-like 1 (cartilage glycoprotein-39); chitinase-3-like protein 1; GP-39; CGP-39; cartilage glycoprotein 39; chitinase 3-like 1 protein; MGC109420;
Gene ID : 89824
mRNA Refseq : NM_053560
Protein Refseq : NP_446012
UniProt ID : Q9WTV
Chromosome Location : 13q13
Pathway : Amino sugar and nucleotide sugar metabolism, organism-specific biosystem; Amino sugar and nucleotide sugar metabolism, conserved biosystem;
Function : catalytic activity; cation binding; chitin binding; chitin binding; chitinase activity; NOT chitinase activity; molecular_function; sugar binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Is there any other mode of action for CHI3L1? 01/05/2022

In addition to being involved in cartilage metabolism and immune regulation, CHI3L1 may also have other modes of action, such as regulating cell adhesion and migration.

What is the role of CHI3L1 in immune regulation? 07/11/2021

This protein can act as an immunomodulator to inhibit the inflammatory response and the activity of immune cells, thereby maintaining the balance of the immune system.

Does CHI3L1 involved in the metabolism and repair of cartilage? 04/15/2021

CHI3L1 can bind to receptors on the surface of chondrocytes, stimulate the proliferation and differentiation of chondrocytes, and promote cartilage synthesis and repair.

How is the expression level of CHI3L1 regulated? 03/20/2021

The expression level of CHI3L1 is regulated by a variety of factors, including transcription factors, signal transduction pathways, and epigenetic modifications.

What is the association between CHI3L1 and joint diseases such as rheumatoid arthritis? 04/26/2020

In joint diseases such as rheumatoid arthritis, the expression level of CHI3L1 may be abnormally elevated, promoting inflammation and joint damage, and aggravating the condition.

How to detect the expression level of CHI3L1? 12/16/2019

The expression level of CHI3L1 can be detected by immunohistochemistry, western blotting, and real-time PCR.

Customer Reviews (3)

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Reviews
12/15/2022

    CHI3L1 has strong biological activity combined with its high purity makes its experimental results extremely reliable.

    10/22/2022

      The band strength in Western blot was high, which improved the signal-to-noise ratio of the experiment.

      10/24/2021

        It can simplify the complex chemical reaction and improve the high yield, shorten the experimental time.

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