Recombinant Rat Chi3l1 protein, His-tagged
Cat.No. : | Chi3l1-1375R |
Product Overview : | Recombinant Rat Chi3l1(Tyr117~Lys364) fused with His tag at N-terminal was expressed in E. coli. |
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Description : | Chi3l1 played an important role in many functions. |
Source : | E. coli |
Species : | Rat |
Tag : | His |
Form : | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300 |
Molecular Mass : | 31.0kD |
Protein length : | Tyr117~Lys364 |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | > 95% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. If bio-activity of the protein is needed, please check active protein |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Reconstitution : | Reconstitute in PBS or others. |
Gene Name : | Chi3l1 chitinase 3-like 1 (cartilage glycoprotein-39) [ Rattus norvegicus ] |
Official Symbol : | Chi3l1 |
Synonyms : | CHI3L1; chitinase 3-like 1 (cartilage glycoprotein-39); chitinase-3-like protein 1; GP-39; CGP-39; cartilage glycoprotein 39; chitinase 3-like 1 protein; MGC109420; |
Gene ID : | 89824 |
mRNA Refseq : | NM_053560 |
Protein Refseq : | NP_446012 |
UniProt ID : | Q9WTV |
Chromosome Location : | 13q13 |
Pathway : | Amino sugar and nucleotide sugar metabolism, organism-specific biosystem; Amino sugar and nucleotide sugar metabolism, conserved biosystem; |
Function : | catalytic activity; cation binding; chitin binding; chitin binding; chitinase activity; NOT chitinase activity; molecular_function; sugar binding; |
Products Types
◆ Recombinant Protein | ||
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CHI3L1-044H | Recombinant Human CHI3L1 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
CHI3L1-1028R | Recombinant Rat CHI3L1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CHI3L1-3219H | Recombinant Human CHI3L1 Protein, MYC/DDK-tagged | +Inquiry |
CHI3L1-1232H | Recombinant Human CHI3L1 Protein, GST-Tagged | +Inquiry |
◆ Lysates | ||
CHI3L1-2521HCL | Recombinant Human CHI3L1 cell lysate | +Inquiry |
CHI3L1-1715MCL | Recombinant Mouse CHI3L1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionIn addition to being involved in cartilage metabolism and immune regulation, CHI3L1 may also have other modes of action, such as regulating cell adhesion and migration.
This protein can act as an immunomodulator to inhibit the inflammatory response and the activity of immune cells, thereby maintaining the balance of the immune system.
CHI3L1 can bind to receptors on the surface of chondrocytes, stimulate the proliferation and differentiation of chondrocytes, and promote cartilage synthesis and repair.
The expression level of CHI3L1 is regulated by a variety of factors, including transcription factors, signal transduction pathways, and epigenetic modifications.
In joint diseases such as rheumatoid arthritis, the expression level of CHI3L1 may be abnormally elevated, promoting inflammation and joint damage, and aggravating the condition.
The expression level of CHI3L1 can be detected by immunohistochemistry, western blotting, and real-time PCR.
Customer Reviews (3)
Write a reviewCHI3L1 has strong biological activity combined with its high purity makes its experimental results extremely reliable.
The band strength in Western blot was high, which improved the signal-to-noise ratio of the experiment.
It can simplify the complex chemical reaction and improve the high yield, shorten the experimental time.
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