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Recombinant Rat Fas protein, His-tagged

Cat.No. : Fas-486R
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  • Gene Information
  • Related Products
Product overview : Recombinant Rat Fas (Q63199) aa. (Gln22~Leu171) fused with His tag was produced in HEK293F cells.
Description : Tnfsf6/Fasl receptor.
Source : HEK293F
Species : Rat
Tag : His
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 18.5kDa; Accurate Molecular Mass: 23kDa as determined by SDS-PAGE reducing conditions.
Protein length : Gln22~Leu171
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : > 90%
Characteristic : Isoelectric point is 6.2.
Applications : SDS-PAGE; WB; ELISA; IP; CoIP; EMSA; Reporter Assays; Purification; Amine Reactive Labeling
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Concentration : 200ug/mL
Storage buffer : 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 5% Trehalose and Proclin300.
Reconstitution : Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex
Gene Name : Fas Fas cell surface death receptor [ Rattus norvegicus (Norway rat) ]
Official Symbol : Fas
Synonyms : Fas; Fas cell surface death receptor; Tnfrsf6; tumor necrosis factor receptor superfamily member 6; CD95 antigen; FASLG receptor; Fas (TNF receptor superfamily, member 6); Fas antigen (ATP1); Fas receptor; Tumor necrosis factor receptor superfamily, member 6; apo-1 antigen; apoptosis-mediating surface antigen FAS
Gene ID : 246097
mRNA Refseq : NM_139194.2
Protein Refseq : NP_631933.2
UniProt ID : Q63199

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Does FAS protein play a role in cell signaling? 10/30/2022

FAS protein plays an important role in cell signaling, it can activate downstream signaling pathways, such as death signaling pathway and survival signaling pathway, by binding to its ligand and transmitting signals.

Why apply knowledge of FAS proteins to clinical practice? 06/27/2022

It can provide a reference for clinical practice and guide the diagnosis, treatment and prevention of diseases by detecting the expression level of FAS protein and understanding its mechanism of action.

How can diseases associated with FAS protein be prevented and treated? 05/13/2022

FAS protein-related diseases can be prevented and treated by regulating the expression level of FAS protein and inhibiting its signaling pathway.

How can gene knockout or knockdown techniques be used to study the function of FAS proteins? 03/31/2021

Gene knockout or knockdown techniques can be used to study the function and mechanism of action of FAS proteins. By knocking out or knocking down the FAS gene, changes in processes such as apoptosis and immune response can be observed to further understand its function and mechanism of action.

What is the role of FAS protein in apoptosis? 09/29/2020

FAS protein can bind to its ligand, activate the death signaling pathway, and induce apoptosis.

How can FAS protein be used to predict disease prognosis? 06/19/2020

The expression level and activity of FAS protein can be measured to predict the prognosis and development trend of certain diseases.

Customer Reviews (3)

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Reviews
09/07/2022

    When experimenting with FAS, the results are very reproducible.

    07/29/2022

      The stability of FAS products allows them to cope with different experimental conditions and modes of operation.

      09/20/2021

        FAS has high specific activity and can exert strong biological effect at low concentration.

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