Recombinant Rat Il1a protein, His-tagged

• Cat.No.: Il1a-75R
• Product Overview: Recombinant rat IL1A, fused to His-tag at N-terminus was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: IL1A also known as interleukin-1 alpha. IL1A belongs to the interleukin 1 cytokine family. IL1A is part of Interleukin-1. IL1 stimulates thymocyte proliferation by inducing IL2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL1 proteins are involved in the inflammatory response, especially IL1A is an early and important mediator of inflammation after injury.
• Source: E. coli
• Species: Rat
• Tag: His
• Form: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol
• Molecular Mass: 20.2kDa (179aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSSAPHSFQ NNLRYKLIRI VKQEFIMNDS LNQNIYVDMD RIHLKAASLN DLQLEVKFDM YAYSSGGDDSKYPVTLKVSN TQLFVSAQGE DKPVLLKEIP ETPKLITGSE TDLIFFWEKI NSKNYFTSAA FPELLIATKE QSQVHLARGL PSMIDFQIS
• Purity: >95% by SDS - PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by Absorbance at 280nm)

Gene Information

• Gene Name: Il1a interleukin 1 alpha [ Rattus norvegicus ]
• Official Symbol: Il1a
• Synonyms: IL1A; interleukin 1 alpha; interleukin-1 alpha; IL-1 alpha
• Gene ID: 24493
• mRNA Refseq: NM_017019
• Protein Refseq: NP_058715
• Pathway: Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Cytokines and Inflammatory Response (BioCarta), organism-specific biosystem; FAS pathway and Stress induction of HSP regulation, organism-specific biosystem; Graft-versus-host disease, organism-specific biosystem
• Function: copper ion binding; copper ion binding; cytokine activity; cytokine activity; interleukin-1, Type I receptor binding