Recombinant Rat Lag3 protein, His-tagged

• Cat.No.: Lag3-1832R
• Product Overview: Recombinant Rat LAG3 /CD223 Protein (Rat LAG3 / CD223) Gly 24 - Leu 442 (Accession # NP_997678) was produced in human 293 cells (HEK293).

Specification

• Description: Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.
• Source: HEK293
• Species: Rat
• Tag: His
• Predicted N Terminal: Gly 24
• Form: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose.
• Molecular Mass: Rat LAG3 / CD223 is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 47.6 kDa. DTT-reduced Protein migrates as 55 kDa in SDS-PAGE due to glycosylation.
• Protein length: AA Gly 24 - Leu 442
• Endotoxin: Less than 1.0 EU per μg of the Rat LAG3 / CD223 by the LAL method.
• Purity: >90% as determined by SDS-PAGE.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4°C); After reconstitution under sterile conditions for 3 months (-70°C).
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: Lag3 lymphocyte activating 3 [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Lag3
• Synonyms: CD223; lymphocyte-activation gene 3
• Gene ID: 297596
• mRNA Refseq: NM_212513.2
• Protein Refseq: NP_997678.2
• UniProt ID: Q5BK54