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Active Recombinant Rat NTRK2 Protein, His-tagged

Cat.No. : NTRK2-1095R
Product Overview : Recombinant rat NTRK2 (Q63604-Isoform T1) (Met1-His429) was expressed with a polyhistidine tag at the C-terminus.
  • Specification
  • Gene Information
  • Related Products
Source : HEK293
Species : Rat
Tag : His
Predicted N Terminal : Cys 32
Form : Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol.
Bio-activity : Measured by its binding ability in a functional ELISA. Immobilized rat NTRK2-His at 10 μg/ml (100 μl/well) can bind biotinylated mouse BDNF, The EC50 of biotinylated mouse BDNF is 12.2-28.6 ng/ml.
Molecular Mass : The recombinant rat NTRK2 comprises 409 amino acids and predicts a molecular mass of 47.1 kDa. The apparent molecular mass of the recombinant protein is approximately 67 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >95 % as determined by SDS-PAGE.
Stability : Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage : Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 [ Rattus norvegicus ]
Official Symbol : NTRK2
Synonyms : NTRK2; neurotrophic tyrosine kinase, receptor, type 2; BDNF/NT-3 growth factors receptor; trk-B; GP145-TrkB/GP95-TrkB; trkB tyrosine kinase; Neural receptor protein-tyrosine kinase (trkB); Tkrb; trkB; TRKB1; RATTRKB1;
Gene ID : 25054
mRNA Refseq : NM_001163168
Protein Refseq : NP_001156640
MIM :
UniProt ID :
Pathway : ARMS-mediated activation, organism-specific biosystem; Activation of TRKA receptors, organism-specific biosystem; Frs2-mediated activation, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, conserved
Function : ATP binding; brain-derived neurotrophic factor binding; brain-derived neurotrophic factor binding; brain-derived neurotrophic factor binding; brain-derived neurotrophic factor-activated receptor activity; brain-derived neurotrophic factor-activated recept

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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