Recombinant Rat Pcsk1 protein, His-tagged

• Cat.No.: PCSK1-4305R
• Product Overview: Recombinant Rat Pcsk1(111-752 aa) fused with His tag was expressed in HEK293.

Specification

• Source: HEK293
• Species: Rat
• Tag: His
• Form: Tris-based buffer,50% glycerol
• Protein length: 111-752 aa
• AA Sequence: SVPRDSALNL FNDPMWNQQW YLQDTRMTAS LPKLDLHVIP VWQKGITGKG VVITVLDDGL EWNHTDIYAN YDPEASYDFN DNDHDPFPRY DPTNENKHGT RCAGEIAMQA NNHKCGVGVA YNSKVGGIRM LDGIVTDAIE ASSIGFNPGH VDIYSASWGP NDDGKTVEGP GRLAQKAFEY GVKQGRQGKG SIFVWASGNG GRQGDNCDCD GYTDSIYTIS ISSASQQGLS PWYAEKCSST LATSYSSGDY TDQRITSADL HNDCTETHTG TSASAPLAAG IFALALEANP NLTWRDMQHL VVWTSEYDPL ANNPGWKKNG AGLMVNSRFG FGLLNAKALV DLADPRTWRN VPEKKECIIK DNNFEPRALK ANGEVIVEIP TRACEGQENA INSLEHVQFE ATIEYSRRGD LHVTLTSAAG TSTVLLAERE RDTSPNGFKN WDFMSVHTWG ENPVGTWTLK VTDMSGRMQN EGRIVNWKLI LHGTSSQPEH MKQPRVYTSY NTVQNDRRGV EKMVNVVEEK PTQNSLNGNL LVPKNSSSSS VEDRRDEQVQ GAPSKAMLRL LQSAFSKNTP SKQSSKIPSA KLSVPYEGLY EALEKLNKPS QLEDSEDSLY SDYVDVFYNT KPYKHRDDRL LQALMDILNE KN
• Purity: >90% ( SDS-PAGE )
• Storage: Store at -20 centigrade, for extended storage, conserve at -20 centigrade or -80 centigrade. Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.

Gene Information

• Gene Name: Pcsk1 proprotein convertase subtilisin/kexin type 1 [ Rattus norvegicus ]
• Official Symbol: Pcsk1
• Synonyms: PCSK1; proprotein convertase subtilisin/kexin type 1; neuroendocrine convertase 1; NEC 1; prohormone convertase 1; prohormone convertase 3; proprotein convertase 1; Protein convertase subtilisin / kexin type I; Protein convertase subtilisin / kexin, type I; BDP; PC1; PC3
• Gene ID: 25204
• mRNA Refseq: NM_017091
• Protein Refseq: NP_058787
• UniProt ID: P28840
• Chromosome Location: 2q11-q12
• Pathway: Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; Incretin Synthesis, Secretion, and Inactivation, organism-specific biosystem; Insulin Synthesis and Processing, organism-specific biosystem; Integration of energy metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem
• Function: chaperone binding; endopeptidase activity; endopeptidase activity; endopeptidase activity; insulin binding; peptidase activity; protein complex binding; serine-type endopeptidase activity; serine-type endopeptidase activity