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Recombinant Rat Pdcd1 protein, His & GST-tagged

Cat.No. : Pdcd1-840R
Product Overview : Recombinant Rat Pdcd1 aa. (Pro39~Ser266 (Accession # D3ZIN8)) fused with N-terminal His & GST tag was produced in E. coli cells.
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  • Gene Information
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Source : E. coli
Species : Rat
Tag : His & GST
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 57.4kDa
Protein length : Pro39~Ser266 (Accession # D3ZIN8)
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 6.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : Pdcd1 programmed cell death 1 [ Rattus norvegicus (Norway rat) ]
Official Symbol : Pdcd1
Synonyms : programmed cell death protein 1-like; programmed cell death protein 1
Gene ID : 301626
mRNA Refseq : NM_001106927.1
Protein Refseq : NP_001100397.1
UniProt ID : D3ZIN8

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (14)

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What are the mechanisms by which PDCD1 modulates the immune response to viral infections? 07/31/2022

PDCD1 modulates responses to viral infections, affecting T cell function and viral clearance.

What are the mechanisms by which PDCD1 modulates the immune response to viral infections? 11/09/2021

PDCD1 modulates responses to viral infections, affecting T cell function and viral clearance.

What role does PDCD1 play in the development of immune tolerance? 10/15/2021

PDCD1 helps develop immune tolerance, preventing overactive immune responses.

How does PDCD1 influence the balance between immune activation and autoimmunity? 05/23/2021

PDCD1 maintains a balance between immune response and autoimmunity, preventing self-reactivity.

How does PDCD1 contribute to the exhaustion of T cells in chronic infections and cancer? 08/13/2020

PDCD1 contributes to T cell exhaustion in chronic diseases and cancers, reducing immune efficacy.

How does PDCD1 influence the balance between immune activation and autoimmunity? 08/05/2020

PDCD1 maintains a balance between immune response and autoimmunity, preventing self-reactivity.

What is the impact of PDCD1 on the effectiveness of immunotherapy in treating cancers? 12/05/2019

PDCD1's role in immunotherapy is pivotal, as blocking PD-1 enhances anti-tumor responses.

How does PDCD1 contribute to the exhaustion of T cells in chronic infections and cancer? 11/21/2019

PDCD1 contributes to T cell exhaustion in chronic diseases and cancers, reducing immune efficacy.

How does PDCD1 (PD-1) regulate immune checkpoint pathways in T cells? 04/24/2019

PDCD1 regulates T cell activity by inhibiting immune responses, crucial in immune checkpoints.

What is the impact of PDCD1 on the effectiveness of immunotherapy in treating cancers? 01/19/2019

PDCD1's role in immunotherapy is pivotal, as blocking PD-1 enhances anti-tumor responses.

What role does PDCD1 play in the development of immune tolerance? 12/08/2018

PDCD1 helps develop immune tolerance, preventing overactive immune responses.

How do alterations in PDCD1 expression or signaling affect autoimmune disease progression? 06/24/2018

Changes in PDCD1 signaling impact autoimmune disease progression, influencing immune system activity.

How does PDCD1 (PD-1) regulate immune checkpoint pathways in T cells? 06/24/2018

PDCD1 regulates T cell activity by inhibiting immune responses, crucial in immune checkpoints.

How do alterations in PDCD1 expression or signaling affect autoimmune disease progression? 02/06/2018

Changes in PDCD1 signaling impact autoimmune disease progression, influencing immune system activity.

Customer Reviews (3)

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Reviews
06/06/2021

    Timely antibody validation, a valuable asset for our laboratory.

    02/12/2021

      Precise protein quantification, fundamental for maintaining data accuracy.

      06/20/2019

        Dependable peptide synthesis, accelerates our peptide-based projects effectively.

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