Recombinant Full Length Human LIN28A Protein, Tag Free
Cat.No. : | LIN28A-1577H |
Product Overview : | Recombinant Human LIN28A Protein (Full Length) without tag was expressed in E. coli. |
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Description : | This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues. |
Source : | E.coli |
Species : | Human |
Form : | Liquid |
Molecular Mass : | ~24 kDa |
Purity : | ≥95% by SDS-PAGE |
Applications : | WB |
Storage : | Short Term Storage: -80 centigrade Long Term Storage: -80 centigrade |
Storage Buffer : | In 20mM TRIS, pH 7.2, containing 200mM sodium chloride and 5mM diothiothreitol (DTT). |
Handling : | After reconstitution, prepare aliquots and staore at -80 centigrade. Avoid freeze/thaw cycles. |
Shipping : | Shipped on Dry Ice |
Gene Name : | LIN28A lin-28 homolog A [ Homo sapiens (human) ] |
Official Symbol : | LIN28A |
Synonyms : | LIN28A; lin-28 homolog A; CSDD1; LIN28; LIN-28; ZCCHC1; lin-28A; protein lin-28 homolog A; RNA-binding protein LIN-28; zinc finger CCHC domain-containing protein 1; zinc finger, CCHC domain containing 1 |
Gene ID : | 79727 |
mRNA Refseq : | NM_024674 |
Protein Refseq : | NP_078950 |
MIM : | 611043 |
UniProt ID : | Q9H9Z2 |
Products Types
◆ Recombinant Protein | ||
Lin28a-3785M | Recombinant Mouse Lin28a Protein, Myc/DDK-tagged | +Inquiry |
LIN28A-643H | Recombinant Human LIN28A Protein | +Inquiry |
LIN28A-29947TH | Recombinant Human LIN28A Protein | +Inquiry |
LIN28A-08H | Recombinant Human LIN28A Protein (2-209), N-FLAG/Avi-tagged, Biotined | +Inquiry |
LIN28A-1296H | Recombinant Human LIN28A Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
LIN28A-4734HCL | Recombinant Human LIN28A 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThe role of LIN28A in disease can be assessed through in-depth analysis of the patient's genomic data and combined with the results of studies in cell and animal models. This can help doctors better understand the patient's condition and develop more effective treatment plans.
Certain biomolecules can be used as molecular markers of LIN28A, such as mRNA or protein of LIN28A detected in biological samples such as blood and urine. These markers can be used for early diagnosis of disease, prognostic judgment, or monitoring of treatment efficacy.
In clinical practice, treatment strategies related to LIN28A need to consider the patient's specific condition, genotype, and treatment goals. Doctors can develop a personalized treatment plan based on the patient's actual situation to improve the treatment effect and maximize the patient's quality of life. At the same time, long-term follow-up and studies are needed to assess the effectiveness and safety of treatment strategies.
The function of LIN28A can be studied through cell models and animal models. For example, the expression of LIN28A can be manipulated by gene knockout or overexpression techniques and then observed for its effects on cell biology and animal behavior.
Therapeutic strategies for LIN28A include inhibiting its expression, modulating its activity, or using gene therapy. For example, some small molecule inhibitors can inhibit the activity of LIN28A, thereby treating some LIN28A-related diseases.
The effect of LIN28A on disease can be predicted by comparing the expression level, sequence, and structure in different disease tissues and normal tissues. This could help scientists better understand the role of LIN28A in disease.
Customer Reviews (3)
Write a reviewLIN28A is green and environmentally friendly, and has little harm to the human body.
It is easy to adhere to the surface of the material, reducing the loss of reagents and reducing costs.
The preparation cost is low and cost-effective.
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