"Methyltransferase" Related Products

Universal Methyltransferase Activity Assay Kit

Cat.No.: Kit-0468
Product Overview: Universal Methyltransferase Activity Assay Kit is a homogeneous mix-and-read fluorescent assay for the determination of any S-adenosyl-L-methionine (AdoMet/SAM) dependent methyltransferase activity. It is suitable for end-point or kinetic read options, which is ideal for determining mechanism of action, kinetics, and screening candidate compounds. The assay is amendable to HTS and miniaturization. The kit is a complete kit for the screening of candidate compounds that may alter normal methyltransferase activity.
Size: 1 x 96 tests
Description: Methylation of proteins, nucleic acids and oligosaccharides is an important post-translational regulatory event. Activities that are methylation-related include meiosis, biosynthesis, development, signal transduction, chromatin regulation, and gene silencing. The enzymes that mediate the covalent transfer of a methyl group from a donor to an acceptor molecule are methyltransferases. Methyltransferases have structurally unrelated acceptors as diverse as proteins and DNA, however frequently use S-adenosylmethionine as a universal donor. Part of the acceptor diversity of this enzyme family relates to the flexible structural folds that bind these molecules in proximity of the donor. The side-chains of lysine, arginine, glutamate, glutamine, asparagines, and isoprenylated residues serve as methylation sites in proteins like histones. Changes in methylation patterns have been tightly linked to disease states such as cancer and vascular disease.
Applications: Functional Studies more details
Kit Components: Components: 1 x 96 tests; Black Microtiter Plate: 1 unit; Methyltransferase Positive Control: 1 x 0.2ml; Methyltransferase Reaction Buffer Concentrate: 1 x 0.3ml; Plate Sealer: 1 x 3 units; Transferase Assay Buffer Concentrate: 1 x 15ml; Transferase Detection Solution Concentrate: 1 x 0.15ml
Compatible Sample Types: Purified protein

Online Inquiry

Note: There will be extra charge for optional service!
Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information


Price does not include shipping and packaging costs.Request quote for final price.

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.