Breakthrough! Scientists Decipher The Fifteen Years’ Unresolved Secrets of IL-23, Revealed The Key Mechanism of Autoimmune Disease!

Protein_IL23A

Recently an international team led by Professor Savvas Savvides at the VIB-UGent Inflammatory Research Center revealed the key molecular mechanisms of autoimmune and inflammatory diseases including psoriasis, rheumatoid arthritis, and Crohn’s disease. By focusing on the immunomodulatory factor IL-23, they found that its proinflammatory activity is strongly dependent on its receptor IL-23R for its structural activation. The research was published in Immunity recently.   Psoriasis, rheumatoid arthritis, inflammatory bowel disease…

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Is That True, Women Are More Likely to Survive Than Men?

Current research shows that women live longer than men. And a recent study found baby girls are more likely to survive in famine, epidemics and other unfortunate circumstances, why this happened? The research found that advantage of women may have existed very early.   Researchers believe that despite the small differences in gender behavior in infancy, the fact that women also have the advantage in infancy suggests that biology, at…

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Browning of Subcutaneous White Adipose Tissue Provides Outstanding Opportunity for Treatment of Obesity

convert white fat to brown fat

In a recent study published in the Journal of Experimental Medicine, researchers from Caroline College and other institutions studied mice to elucidate the molecular mechanism of conversion of energy-storing white fat into energy-consuming brown one.   Obesity is a major health problem for the global population, affecting people of all ages and increasing the risk of many diseases in humans, including cardiovascular disease, type 2 diabetes and cancers; although obesity…

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Scary! Pressure Will Accelerate The Occurrence of Malignant Pancreatic Cancer!

Pancreas

In a recent study published in the journal Cancer Cell, researchers from Columbia University Medical Center found that stress may accelerate the development of pancreatic cancer by stimulating the release of “fighting or running away” hormones, β-blockers that inhibit these hormones can effectively increase the survival of cancer-bearing mouse models. In addition, researchers analyzing patients with malignant pancreatic cancer found that patients taking selective β-blockers survived two-thirds more than the…

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New Drug Resistance Mechanism Found Through Persevere Research of Prostate Cancer

prostate cancer

Most tumor growing can stop after long-time medicine intake, and even it can become smaller or finally disappear. But what made the doctors struggling was that a few months later cancer cells gradually developed resistance and the tumor was once again deteriorating and menacing. Without good second-line anti-cancer drugs, physicians and patients really can do nothing. However, with the persevering efforts of scientists, we have the opportunity to gain the…

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