Johnson & Johnson recently announced that the company has stopped a clinical trial of a new Alzheimer’s disease drug due to certain safety issues. This is another failed clinical trial following the announcement of several large clinical trials that have no effect in treating Alzheimer’s disease. More and more failure cases tell us that we need to stop and think about how we could find the cause of Alzheimer’s disease….
Day: August 9, 2018
Nat Med: Key Factors Determining the Anticancer Effect of Immunological Checkpoint Therapy
Stimulatory dendritic cells (SDCs) play a key role in stimulating cytotoxic T lymphocytes and promoting immune responses against cancer. Studying the mechanisms that regulate the abundance of SDCs in the tumor microenvironment (TME) will provide new therapeutic strategies. Rencently, researchers from the University of California, San Francisco, studied the abundance in human melanoma and the influencing factors of SDC, and found it was associated with intratumoral expression of…