Calcineurin Phosphatase assay Kit
Cat.No. : | Kit-0135 |
Product Overview : | Safe and non-radioactive assayConventient 1-step detection, no mixing neededHigh throughput with 96 well plate format |
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- Gene Information
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Size : | 96 wells |
Applications : | Colorimetric detection, HTS |
Storage : | -80°C |
Products Types
◆ Assay kits | ||
Kit-0150 | Cellular Calcineurin Phosphatase Activity Colorimetric Assay Kit | +Inquiry |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionCalcineurin is involved in dephosphorylating proteins that play a role in synaptic plasticity, which is crucial for learning and memory.
Calcineurin is a target for immunosuppressive drugs like cyclosporine and tacrolimus, which inhibit its activity. This is important in preventing organ transplant rejection and treating autoimmune diseases.
Side effects may include increased susceptibility to infections and kidney toxicity. Long-term use may lead to adverse effects, and not all patients respond to these drugs.
Calcineurin is a heterodimeric protein composed of a catalytic subunit (CnA) and a regulatory subunit (CnB). It interacts with calcium ions and calmodulin, which bind to CnB, activating the phosphatase activity of CnA.
Calcineurin is a key component of the T cell receptor signaling pathway. It activates transcription factors like NFAT, which control the expression of genes involved in the immune response.
Customer Reviews (3)
Write a reviewThe product I ordered arrived promptly, and I'm impressed with the efficiency."
I'm thoroughly satisfied with the product, it made my lab work so much easier.
The product I received for my experiments was of the highest quality.
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