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CCR7 HEK 293 β-Arrestin GPCR Assay Kit

Cat.No. : Kit-1159
Product Overview : β-Arrestin GPCR cells are engineered to co-the ProLink (PK) tagged GPCR and the Enzyme Acceptor (EA) tagged β-Arrestin. Activation of the GPCR-PK induces β-Arrestin-EA recruitment, forcing complementation of the two β-galactosidase enzyme fragments (EA and PK). The resulting functional enzyme hydrolyzes substrate to generate a chemiluminescent signal. These cells have been modified to prevent long term propagation and expansion using a proprietary compound that has no apparent effect on assay performance.
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Size : 100 dp(1 x 96-well)/200 dp(2 x 96-well)/1000 dp(10 x 96-well)
Storage : Short term (2 weeks): Store in vapor phase of liquid N2

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How does CCR7 contribute to lymphocyte trafficking and homing? 01/23/2022

It directs T cells and dendritic cells to lymph nodes, ensuring proper immune surveillance.

What therapeutic strategies are being explored targeting CCR7 for disease treatment? 12/24/2021

Therapeutic strategies include targeting CCR7 to modulate immune responses in autoimmune diseases and cancer.

How is CCR7 implicated in cancer progression and metastasis? 07/08/2021

CCR7 can facilitate tumor cell invasion and metastasis to lymph nodes.

What role does CCR7 play in the formation of immune synapses? 03/15/2021

CCR7 helps form immune synapses for effective T cell activation.

What is the main function of CCR7 in the immune system? 03/01/2021

CCR7 guides the migration of various immune cells to lymphoid tissues, aiding in immune responses.

In which cells or tissues is CCR7 predominantly expressed? 06/27/2020

CCR7 is predominantly expressed in T cells, dendritic cells, and various other immune cells.

Are there known genetic mutations or alterations in CCR7 associated with specific diseases? 07/14/2019

Genetic alterations in CCR7 have been linked to certain autoimmune diseases and cancers.

Customer Reviews (3)

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Reviews
10/16/2022

    Perfect for protein research.

    04/05/2022

      Fast delivery, outstanding product.

      03/14/2022

        Product works as intended.

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