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CXCR5 (BLR1) CHO-K1 β-Arrestin GPCR Assay Kit

Cat.No. : Kit-1200
Product Overview : β-Arrestin GPCR cells are engineered to co-the ProLink (PK) tagged GPCR and the Enzyme Acceptor (EA) tagged β-Arrestin. Activation of the GPCR-PK induces β-Arrestin-EA recruitment, forcing complementation of the two β-galactosidase enzyme fragments (EA and PK). The resulting functional enzyme hydrolyzes substrate to generate a chemiluminescent signal. These cells have been modified to prevent long term propagation and expansion using a proprietary compound that has no apparent effect on assay performance.
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Size : 100 dp(1 x 96-well)/200 dp(2 x 96-well)/1000 dp(10 x 96-well)
Storage : Short term (2 weeks): Store in vapor phase of liquid N2

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there any clinical studies targeting CXCR5 protein for therapeutic purposes? 12/21/2022

Yes, there are ongoing clinical studies investigating the use of CXCR5 inhibitors for the treatment of autoimmune diseases.

Is there a genetic component to variations in CXCR5 protein expression? 07/01/2022

Yes, genetic variations can influence the expression and function of CXCR5 protein, contributing to individual differences in immune responses.

Are there any diagnostic tests that measure CXCR5 protein levels? 05/20/2018

Yes, there are research-based diagnostic tests that measure CXCR5 protein levels, but they are not yet widely used in clinical practice.

How is CXCR5 protein involved in the development of lymphoid tissues? 06/27/2017

CXCR5 protein is critical for the organization and development of lymphoid tissues, such as lymph nodes and spleen.

Can CXCR5 protein be used as a biomarker for disease activity? 12/03/2016

Research suggests that CXCR5 protein levels may serve as a biomarker for disease activity in certain autoimmune and inflammatory conditions.

Customer Reviews (3)

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01/25/2022

    Such support ensures researchers have access to reliable tools and expertise, facilitating their investigations into the functions, mechanisms, and disease relevance of CXCR5 protein.

    10/12/2021

      Using CXCR5 protein in trials provides advantages such as its involvement in cellular processes and its disease associations.

      09/27/2021

        A manufacturer can serve as a collaborative partner, engaging in discussions, and exchanging knowledge with researchers.

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