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Cat.No.
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CPBT-53705GH
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Product Overview
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Goat Polyclonal antibody to Human AP1G1.
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Antigen Description
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Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. Two transcript variants encoding different isoforms have been found for this gene.
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Isotype
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IgG
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Immunogen
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Synthetic peptide: CTAPTSKPSSAGGEL, corresponding to amino acids 646 - 659 of Human AP1G1.
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Host
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Goat
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Species
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Human
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Specificity
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Widely expressed.
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Formulation
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Liquid
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Purity Detail
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Immunogen affinity purified
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Applications
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WB, Electron Microscopy
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Storage buffer
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Preservative: 0.01% Sodium AzideConstituents: 0.15M Sodium Chloride, 0.02M Potassium Phosphate. pH 7.2
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Storage
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Shipped at 4oC. Upon delivery aliquot and store at -20oC or -80oC. Avoid repeated freeze / thaw cycles.
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Sequence similarities
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Belongs to the adaptor complexes large subunit family.Contains 1 GAE domain.
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Antigen Gene Information
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Gene Name
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AP1G1 adaptor-related protein complex 1, gamma 1 subunit [ Homo sapiens ]
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Official Symbol
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AP1G1
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Synonyms
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AP1G1; adaptor-related protein complex 1, gamma 1 subunit; AP-1 complex subunit gamma-1; Adapter-related protein complex 1 subunit gamma-1; Adaptor protein complex AP 1 gamma 1 subunit; Adaptor protein complex AP 1 subunit gamma 1; Adaptor protein complex AP-1 subunit gamma-1; Adaptor related protein complex 1 gamma 1 subunit; adaptor-related protein complex 1 gamma 1 subunit; ADTG; AP 1 complex subunit gamma 1; AP-1 complex subunit gamma-1; AP1G1; AP1G1_HUMAN; CLAPG1; Clathrin assembly protein complex 1 gamma 1 large chain; Clathrin assembly protein complex 1 gamma large chain; Clathrin assembly protein complex 1 gamma-1 large chain; Clathrin associated/assembly/adaptor protein large gamma 1; clathrin-associated/assembly/adaptor protein large gamma 1; Gamma1 adaptin; Gamma1-adaptin; Golgi adaptor HA1/AP1 adaptin gamma subunit; Golgi adaptor HA1/AP1 adaptin subunit gamma 1; Golgi adaptor HA1/AP1 adaptin subunit gamma-1; MGC18255; gamma adaptin; gamma1-adaptin; golgi adaptor HA1/AP1 adaptin gamma subunit; adaptor protein complex AP-1 subunit gamma-1; golgi adaptor HA1/AP1 adaptin subunit gamma-1; adapter-related protein complex 1 subunit gamma-1; clathrin assembly protein complex 1 gamma large chain; clathrin assembly protein complex 1 gamma-1 large chain; clathrin-associated/assembly/adaptor protein, large, gamma 1; ADTG; CLAPG1;
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GeneID
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164
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mRNA Refseq
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NM_001030007
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Protein Refseq
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NP_001025178
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Pathway
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Clathrin derived vesicle budding, organism-specific biosystem; Golgi Associated Vesicle Biogenesis, organism-specific biosystem; HIV Infection, organism-specific biosystem; Host Interactions of HIV factors, organism-specific biosystem; Lysosome, organism-specific biosystem;
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Function
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kinesin binding; protein binding; protein transporter activity; transporter activity;
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Download Datasheet:
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