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Cat.No.
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CPBT-54518RH
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Product Overview
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Rabbit Polyclonal antibody to Human HNRNPF.
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Antigen Description
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This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH. Multiple alternatively spliced variants, encoding the same protein, have been identified.
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Isotype
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IgG
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Immunogen
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Synthetic peptide derived from N-terminal of Human hnRNP F.
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Host
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Rabbit
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Species
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Human
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Specificity
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Expressed ubiquitously.
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Formulation
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Liquid
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Purity Detail
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Immunogen affinity purified
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Applications
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WB, ELISA
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Storage buffer
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Preservative: 0.02% Sodium AzideConstituents: 50% Glycerol, PBS, 150mM Sodium chloride, pH 7.4
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Storage
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Store at -20oC. Stable for 12 months at -20oC
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Sequence similarities
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Contains 3 RRM (RNA recognition motif) domains.
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Antigen Gene Information
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Gene Name
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HNRNPF heterogeneous nuclear ribonucleoprotein F [ Homo sapiens ]
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Official Symbol
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HNRNPF
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Synonyms
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HNRNPF; heterogeneous nuclear ribonucleoprotein F; HNRPF; N-terminally processed; Heterogeneous nuclear ribonucleoprotein F; hnRNP F; HnRNP F protein; HNRNPF; hnRP F; hnRPF; HNRPF_HUMAN; mcs94 1; MGC110997; Nucleolin like protein; Nucleolin like protein mcs94 1; Nucleolin-like protein mcs94-1; OK/SW cl.23; OK/SW-cl.23; OTTHUMP00000019482; OTTHUMP00000043413; OTTHUMP00000043414; Ribonucleoprotein F; HnRNP F protein; nucleolin-like protein mcs94-1; mcs94-1; OK/SW-cl.23;
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GeneID
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3185
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mRNA Refseq
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NM_001098204
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Protein Refseq
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NP_001091674
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MIM
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601037
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Uniprot ID
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P52597
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Chromosome Location
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10q11.21
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Pathway
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Formation and Maturation of mRNA Transcript, organism-specific biosystem; Gene Expression, organism-specific biosystem; Processing of Capped Intron-Containing Pre-mRNA, organism-specific biosystem; mRNA Processing, organism-specific biosystem; mRNA Splicing, organism-specific biosystem;
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Function
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RNA binding; nucleotide binding; protein binding; single-stranded RNA binding;
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Download Datasheet:
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