Recombinant Human MYL6 protein, His-tagged

• Cat.No.: MYL6-3446H
• Product Overview: Recombinant Human MYL6(1-151aa) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: Myosin light polypeptide 6 is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain that is expressed in smooth muscle and non-muscle tissues. MYL6 participates in generating the force for cellular movements, thereby playing an important role in overall cellular function.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
• Molecular Mass: 19.1 kDa (171aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSHLPMLQTVAKN KDQGTYEDYV EGLRVFDKEG NGTVMGAEIR HVLVTLGEKM TEEEVEMLVA GHEDSNGCIN YEELVRMVLN G MCDFTEDQTA EFKEAFQLFD RTGDGKILYS QCGDVMRALG QNPTNAEVLK VLGNPKSDEM NVKVLDFEHF
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle [ Homo sapiens ]
• Official Symbol: MYL6
• Synonyms: MYL6; myosin, light chain 6, alkali, smooth muscle and non-muscle; myosin, light polypeptide 6, alkali, smooth muscle and non muscle; myosin light polypeptide 6; ESMLC; MLC1SM; MLC3NM; myosin light chain A3; 17 kDa myosin light chain; myosin light chain alkali 3; myosin, light polypeptide 6, alkali, smooth muscle and non-muscle; LC17; LC17A; LC17B; MLC-3; MLC3SM; LC17-GI; LC17-NM
• Gene ID: 4637
• mRNA Refseq: NM_079423
• Protein Refseq: NP_524147
• MIM: 609931
• UniProt ID: P60660
• Chromosome Location: 12q13.13
• Pathway: Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Focal Adhesion, organism-specific biosystem; Muscle contraction, organism-specific biosystem; Sema4D in semaphorin signaling, organism-specific biosystem; Sema4D induced cell migration and growth-cone collapse, organism-specific biosystem; Semaphorin interactions, organism-specific biosystem
• Function: actin-dependent ATPase activity; calcium ion binding; motor activity; protein binding; structural constituent of muscle