Recombinant Human MTHFS protein, His-tagged
Cat.No. : | MTHFS-3464H |
Product Overview : | Recombinant Human MTHFS(1-203aa) fused with His tag at N-terminal was expressed in E. coli. |
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- Gene Information
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Description : | MTHFS, also known as 5-formyltetrahydrofolate cyclo-ligase, is a cytosolic protein involved in the formate metabolic process. MTHFS, with a magnesium cofactor, catalyzes the ATP-dependent reaction that reduces 5-formyltetrahydrofolate (5-MTHF) to 5,10-methenyltetrahydrofolate(MTHF). MTHF is the substrate used by MTHFR (methylenetetrahydrofolate reductase) to generate 5-MTHF. MTHF is also a coenzyme used in thymidine biosynthesis by thymidylate synthase (FAD). |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 30% glycerol, 0.2M NaCl |
Molecular Mass : | 25.4kDa (223aa) confirmed by MALDI-TOF |
AA Sequence : | MGSSHHHHHH SSGLVPRGSHIFQRGKICFI PRYRFQSNHM DMVRIESPEE ISLLPKTSWN IPQPGEGDVR EEALSTGGLD LIFMPGLGFD KHGNRLGRGK GYYDAYLKRCMAAAAVSSAK RSLRGELKQR LRAMSAEERL RQSRVLSQKV IAHSEYQKSK RISIFLSMQD EIETEEIIKDLQHQEVKPYT LALAFKEQIC LQVPVNENDM KVDEVLYEDS STA |
Purity : | >95% by SDS - PAGE |
Storage : | Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5 mg/ml (determined by Bradford assay) |
Gene Name : | MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) [ Homo sapiens ] |
Official Symbol : | MTHFS |
Synonyms : | MTHFS; 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase); 5-formyltetrahydrofolate cyclo-ligase; HsT19268; methenyl-THF synthetase; FLJ30410; |
Gene ID : | 10588 |
mRNA Refseq : | NM_006441 |
Protein Refseq : | NP_006432 |
MIM : | 604197 |
UniProt ID : | P49914 |
Chromosome Location : | 15q24.3 |
Pathway : | Metabolic pathways, organism-specific biosystem; One Carbon Metabolism, organism-specific biosystem; One carbon pool by folate, organism-specific biosystem; One carbon pool by folate, conserved biosystem; |
Function : | 5-formyltetrahydrofolate cyclo-ligase activity; 5-formyltetrahydrofolate cyclo-ligase activity; ATP binding; folic acid binding; ligase activity; nucleotide binding; |
Products Types
◆ Recombinant Protein | ||
MTHFS-5781M | Recombinant Mouse MTHFS Protein, His (Fc)-Avi-tagged | +Inquiry |
MTHFS-5706H | Recombinant Human MTHFS Protein, GST-tagged | +Inquiry |
MTHFS-2719R | Recombinant Rhesus Macaque MTHFS Protein, His (Fc)-Avi-tagged | +Inquiry |
MTHFS-01H | Recombinant Human MTHFS Protein, Myc/DDK-tagged | +Inquiry |
MTHFS-3914H | Recombinant Human MTHFS Protein (Met1-Ala203), C-His tagged | +Inquiry |
◆ Lysates | ||
MTHFS-4080HCL | Recombinant Human MTHFS 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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