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Cat. No. |
SRI-3478H |
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Product Overview |
Recombinant human SRI
protein, fused to His-tag at N-terminus, was expressed in E.coli and
purified by using conventional chromatography. |
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Description |
Sorcin, also known as
SRI, is a 22-kDa calcium-binding protein initially identified in
multidrug-resistant cells. SRI modulates excitation-contraction coupling
in the heart and contributes to calcium homeostasis in the heart
sarcoplasmic reticulum. |
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Form |
Liquid. 20mM Tris-HCl
buffer (pH8.0) containing 40% glycerol, 0.2M NaCl, 1mM DTT, 0.1mM PMSF |
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Molecular Weight |
24.1 kDa (221aa)
confirmed by MALDI-TOF |
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Purity |
> 90% by SDS - PAGE |
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Concentration |
0.5 mg/ml (determined
by Bradford assay) |
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Sequences of amino
acids |
MGSSHHHHHH SSGLVPRGSH
MGSMAYPGHP GAGGGYYPGG YGGAPGGPAF PGQTQDPLYG YFAAVAGQDG QIDADELQRC
LTQSGIAGGY KPFNLETCRL MVSMLDRDMS GTMGFNEFKE LWAVLNGWRQ HFISFDTDRS
GTVDPQELQK ALTTMGFRLS PQAVNSIAKR YSTNGKITFD DYIACCVKLR ALTDSFRRRD
TAQQGVVNFP YDDFIQCVMS V |
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Storage |
Can be stored at +4oC
short term (1-2 weeks). For long term storage, aliquot and store at
-20oC or -70oC. Avoid repeated freezing and thawing cycles. |
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Gene Information
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Gene Name |
SRI sorcin [ Homo sapiens ] |
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Synonyms |
CP22; SRI; V19; CP-22;
H_RG167B05.1; 22 kDa protein;
calcium binding protein
amplified in mutlidrug-resistant cells; OTTHUMP00000205590; Sorcin; SCN;
FLJ26259;
OTTHUMP00000206386;
OTTHUMP00000213080 |
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GeneID |
6717 |
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mRNA Refseq |
NM_003130 |
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Protein Refseq |
NP_003121 |
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MIM |
182520 |
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UniProt ID |
P30626 |
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Chromosome Location |
7q21.1 |
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Function |
calcium channel
regulator activity; calcium ion binding; receptor binding |
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