"PDCD4" Related Products

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Rabbit Anti-Human PDCD4 Polyclonal Antibody

Cat. No.: CPBT-56409RH
Product Overview: Rabbit Polyclonal antibody to Human PDCD4.
Antigen Description: This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants.
Isotype: IgG
Immunogen: Synthetic peptide conjugated to KLH derived from within residues 350 - 450 of Human PDCD4.
Host: Rabbit
Species: Human
Specificity: Up-regulated in proliferative cells. Highly expressed in epithelial cells of the mammary gland. Reduced expression in lung cancer and colon carcinoma.
Formulation: Liquid
Purity Detail: Immunogen affinity purified
Applications: IP, ICC/IF, WB
Storage buffer: Preservative: 0.02% Sodium AzideConstituents: 1% BSA, PBS, pH 7.4
Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequence similarities: Belongs to the PDCD4 family.Contains 2 MI domains.
Gene Name: PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) [ Homo sapiens ]
Official Symbol: PDCD4
Synonyms: PDCD4; H731; MGC33046; MGC33047; programmed cell death 4 (neoplastic transformation inhibitor); programmed cell death protein 4; protein 197/15a; nuclear antigen H731; neoplastic transformation inhibitor protein; Nuclear antigen H731-like
Gene ID: 27250
mRNA Refseq: NM_014456
Protein Refseq: NP_055271
MIM: 608610
UniProt ID: Q53EL6
Chromosome Location: 10q24
Pathway: mTOR signaling pathway
Function: RNA binding; binding; protein binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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