Rabbit Polyclonal antibody to Human PDCD4.
This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants.
Synthetic peptide conjugated to KLH derived from within residues 350 - 450 of Human PDCD4.
Up-regulated in proliferative cells. Highly expressed in epithelial cells of the mammary gland. Reduced expression in lung cancer and colon carcinoma.
Immunogen affinity purified
IP, ICC/IF, WB
Preservative: 0.02% Sodium AzideConstituents: 1% BSA, PBS, pH 7.4
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Belongs to the PDCD4 family.Contains 2 MI domains.