Catalog # or name ...
Rabbit Polyclonal antibody to Human PDCD4.
This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants.
A synthetic peptide corresponding to amino acids near the carboxyl terminus of human PDCD4 protein
Up-regulated in proliferative cells. Highly expressed in epithelial cells of the mammary gland. Reduced expression in lung cancer and colon carcinoma.
Immunogen affinity purified
WB, ELISA, IHC-P
Preservative: 0.01% Sodium AzideConstituents: 0.15M Sodium chloride, 0.02M Potassium phosphate, pH 7.2
Shipped at 4oC. Upon delivery aliquot and store at -20oC or -80oC. Avoid repeated freeze / thaw cycles.
Belongs to the PDCD4 family.Contains 2 MI domains.
Antigen Gene Information
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) [ Homo sapiens ]
PDCD4; programmed cell death 4 (neoplastic transformation inhibitor); programmed cell death protein 4; H731; nuclear antigen H731; Death up-regulated gene protein; Dug; H731; Ma3; MGC33046; MGC33047; Neoplastic transformation inhibitor; Neoplastic transformation inhibitor protein; Nuclear antigen H731; Nuclear antigen H731 like; Nuclear antigen H731 like protein; Nuclear antigen H731-like; PDCD 4; Pdcd4; PDCD4_HUMAN; Programmed cell death 4; programmed cell death 4 (neoplastic transformation inhibitor); Programmed cell death protein 4; Protein 197/15a; Protein MA-3; RP11 348N5.4; Tis; Topoisomerase-inhibitor suppressed protein; protein 197/15a; neoplastic transformation inhibitor protein;
mTOR signaling pathway, organism-specific biosystem;
RNA binding; binding; protein binding;
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