Recombinant Human DR1, His-tagged
Cat.No. : | DR1-2777H |
Product Overview : | Recombinant human DR1 protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography.MW = 21.6 kDa(196aa). |
- Specification
- Gene Information
- Related Products
Cat. No. : | DR1-2777H |
Description : | DR1, also known as NC2-beta, is a TBP (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. By selectively repressing polymerases II and III, DR1 may shift the physiological balance of transcriptional output in favor of polymerase I. |
Source : | E.coli. |
Form : | Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 100 mM NaCl, 0.1 mM PMSF ,10% Glycerol. |
Purity : | > 85% by SDS - PAGE. |
Concentration : | 0.5 mg/ml (determined by Bradford assay). |
Sequences Of Amino Acids : | MGSSHHHHHH SSGLVPRGSH MASSSGNDDD LTIPRAAINK MIKETLPNVR VAND ARELVV NCCTEFIHLI SSEANEICNK SEKKTISPEHVIQALESLGF GSYISEVKEV LQE CKTVALK RRKASSRLEN LGIPEEELLR QQQELFAKAR QQQAELAQQE WL QMQQAAQQ AQLAAASASA SNQAGSSQDE EDDDDI. |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2) [ Homo sapiens ] |
Synonyms : | DR1; down-regulator of transcription 1, TBP-binding (negative cofactor 2); NC2; NC2-BETA; down-regulator of transcription 1; OTTHUMP00000012557; Protein Dr1; TATA-binding protein-associated phosphoprotein; Negative cofactor 2-beta; NC2-beta |
Gene ID : | 1810 |
mRNA Refseq : | NM_001938 |
Protein Refseq : | NP_001929 |
MIM : | 601482 |
UniProt ID : | Q01658 |
Chromosome Location : | 1p22.1 |
Function : | sequence-specific DNA binding; transcription corepressor activity; transcription factor binding |
Products Types
◆ Recombinant Protein | ||
DR1-2871H | Recombinant Human DR1 Protein, GST-tagged | +Inquiry |
Dr1-2656M | Recombinant Mouse Dr1 Protein, Myc/DDK-tagged | +Inquiry |
DR1-2523M | Recombinant Mouse DR1 Protein, His (Fc)-Avi-tagged | +Inquiry |
DR1-1611R | Recombinant Rat DR1 Protein, His (Fc)-Avi-tagged | +Inquiry |
DR1-1151R | Recombinant Rhesus Macaque DR1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
DR1-6820HCL | Recombinant Human DR1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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