| Description : |
Interleukin 15 (IL-15) is a cytokine with structural similarity to IL-2 that is secreted by mononuclear phagocytes (and some other cells) following infection by virus(es). This cytokine induces cell proliferation of natural killer cells; cells of the innate immune system whose principal role is to kill virally infected cells. IL-15 was discovered to be a member of a family of cytokines, which also includes IL-2, IL-4, IL-7, IL-9, and IL-21. The specific receptor for IL-15, IL-15 receptor alpha, appears to regulate IL-15 secretion, stability, and activity. All members of this family use the common gamma chain as part of their signaling complex. IL-15 has been shown to play a role in many diseases, including obesity, influenza, and inflammatory autoimmune diseases. |
| Source : |
Yeast |
| Species : |
Swine |
| Form : |
Lyophilized without carrier protein. |
| Molecular Mass : |
Swine IL-15 has a predicted molecular weight of 13.1 kDa. |
| AA Sequence : |
TWQHVISDLK KIEDLIRSIH MDATLYTESD AHPNCKVTAM KCFLLELRVI LQESRNSDIS DTVENLIILA NSSLSSIEYK TESGCKECEE LEEKNINEFL KSFIHIVQMF INPS (114) |
| Purity : |
>95% as visualized by SDS-PAGE analysis. |
| Applications : |
The Swine IL-15 protein can be used in cell culture, as an IL-15 ELISA Standard, and as a Western Blot Control. |
| Storage : |
Stable for up to twelve months from date of receipt at -20ºC. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20ºC. Avoid repeated freeze/thaw cycles. |
| Reconstitution : |
Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein. |
