Catalog # or name ...
Rabbit Polyclonal antibody to Human VIM.
This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.
Synthetic peptide derived from internal sequence of human vimentin.
Highly expressed in fibroblasts, some expression in T- and B-lymphocytes, and little or no expression in Burkitts lymphoma cell lines. Expressed in many hormone-independent mammary carcinoma cell lines.
Vimentin is found in connective tissue and in the cytoskeleton.
Immunogen affinity purified
Preservative: 0.02% Sodium AzideConstituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
Shipped at 4oC. Upon delivery aliquot and store at -20oC. Avoid freeze / thaw cycles.
Belongs to the intermediate filament family.
Antigen Gene Information
VIM vimentin [ Homo sapiens ]
VIM; vimentin; FLJ36605; VIM; VIME_HUMAN; vimentin; OTTHUMP00000019224; OTTHUMP00000019225;
Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem; Aurora B signaling, organism-specific biosystem;
identical protein binding; protein C-terminus binding; protein binding; structural constituent of cytoskeleton;
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