Recombinant Human Polo-like Kinase 2 (Drosophila), GST-tagged

• Cat.No.: PLK2-565H
• Product Overview: Recombinant Human full length Plk2 with N-terminal GST tag expressed in aBaculovirus infected Sf9 cellexpression system. MW =107 kDa.

Specification

• Cat. No.: PLK2-565H
• Description: Serine/threonine-protein kinase PLK2 is an enzyme that in humans is encoded by the PLK2 gene. Serum-inducible kinase is a member of the "polo" family of serine/threonine protein kinases that have a role in normal cell division.
• Source: Baculovirus infected Sf9 cell.
• Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
• Purity: >80%.
• Specific Activity: 4.6 pmol/min/μg enzyme reaction is conducted in a buffer containing 50mM HEPES (pH7.5), 10mM MgCl2, 1mM EGTA, 200μM ATP, 0.01% Brij-35 and 2μM substrate (SER/THR 16, Invitrogen) at room temperature for 1 hour.
• Formulated In: 25mM Tris-HCl, pH 8.0, 100mM NaCl, 0.05% Tween-20, 50% glycerol, and 3mM DTT.
• Stability: >6 months at -80°C.

Gene Information

• Gene Name: PLK2 polo-like kinase 2 (Drosophila) [ Homo sapiens ]
• Synonyms: polo-like kinase 2 (Drosophila); SNK; PLK2; serine/threonine-protein kinase PLK2; PLK-2; serum-inducible kinase; serine/threonine-protein kinase SNK;Serum-inducible kinase; polo-like kinase 2; Polo-like kinase 1; EC 2.7.11.21
• Gene ID: 10769
• mRNA Refseq: NM_006622.2
• Protein Refseq: NP_006613.2
• MIM: 607023
• UniProt ID: Q9NYY3
• Chromosome Location: 5q12.1-q13.2
• Function: ATP binding; nucleotide binding; polo kinase kinase activity; protein binding; protein serine/threonine kinase activity; signal transducer activity; transferase activity