Recombinant Human Luteinizing Hormone Beta Polypeptide

Cat. No.

LHB-P015H

Product Overview

Recombinant Human LHB is produced in yeast and the resultant protein is 121 Aa. MW=23.4 KDa.

Description

Recombinanthuman LHB produced in yeast with 2 subunits, alpha =92 residues, beta =121residues.

Background

This gene is a member of the LHBfamily and encodes the beta subunit of luteinizing hormone (LH). LHB isheterodimers consisting of a common alpha subunit and an unique beta subunitwhich confers biological specificity. LHB is expressed in the pituitary glandand promotes spermatogenesis and ovulation by stimulating the testes andovaries to synthesize steroids. The genes for the beta chains of chorionicgonadotropin and for luteinizing hormone are contiguous on chromosome19q13.3. Mutations in this gene are associated with hypogonadism which ischaracterized by infertility and pseudohermaphroditism. The expressionproduct is the active ingredient of Luveris.

Purity

>95%

Source

yeast

Species

Human

Endotoxin

< 1.0 EU per μg of the protein

Sequences of aminoacids

SREPLRPWCHPINAILAVEKEGCPVCITVNTTICAGYCPTMMRVLQAVLPPLPQVVCTYRDVRFESIRLPGC
PRGVDPVVSFPVALSCRCGPCRRSTSDCGGPKDHPLTCDHPQLSGLLFL

CAS number

152923-57-4

Storage

Can be stored at +4^oC short term (1-2weeks). For long term storage, aliquot and store at -20^oC or -70^oC. Avoidrepeated freezing and thawing cycles.

Gene Information