Recombinant Human RELA, C-Terminal Truncated
- Specification
- Gene Information
- Related Products
Cat. No. : | RELA-627TH |
Description : | NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. |
Purity : | The protein was purified by affinity chromatography. The purity is greater than 98.0%. |
Formulation : | Supplied asliquid. 5 ug protein in 10 ul (0.5 ug/ul) in Tris-HCL, 0.2 M NaCl, 2 mM MgCl2, 0.2 mM EDTA, 1M DTT. |
Stability : | For long-term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze-thaw cycles. |
Biological Activity : | The biological activity of this protein or its ability to bind to DNA has not been established. |
Amino Acid Sequence : | MDELFPLIFPAEPAQASGPYVEIIE QPKQRGMRFRYKCEGRSAGSIPGER STDTTKTHPTIKINGYTGPGTVRIS LVTKDPPHRPHPHELVGKDCRDGFY EAELCPDRCIHSFQNLGIQCVKKRD LEQAISQRIQTNNNPFQVPIEEQRG DYDLNAVRLCFQVTVRDPSGRPLRL PPVLPHPIFDNRAPNTAELKICRVN RNSGSCLGGDEIFLLCDKVQKEDIE VYFTGPGWEARGSFSQADVHRQVAI VFRTPPYADPSLQAPVRVSMQLRRP SDRELSEPMEFQYLPDTDDRHRIEE KRKRTYETFKSIMKKSPFSGPTDPR PPPRRIAVPSRSSASVPKPAPQPYP FTSSLSTINYDEFPTMVFPSGQISQ ASALAPAPPQVLPQAPAPAPAPAMV SALAQAPAPVPVLAPGPPQAVAPPA PKPTQAGEGTLSEAL LQLQFDDEDLGALLGNSTDPAVFTD LASVDNSEFQQLLNQGIPVAPHTTE PML MEYPEAITRLVTGAQRPPDPAPAPL GAPGLPNGLLSGDEDFSSI |
Publication : |
Quantitation of the Dynamic Profiles of the Innate Immune Response Using Multiplex Selected Reaction Monitoring–Mass Spectrometry (2013)
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Gene Name : | RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) [ Homo sapiens ] |
Official Symbol : | RELA |
Synonyms : | RELA; v-rel reticuloendotheliosis viral oncogene homolog A (avian); p65; NFKB3; transcription factor p65; NF-kappa-B p65delta3; nuclear factor NF-kappa-B p65 subunit; nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 ;OTTHUMP00000233474; OTTHUMP00000233475; OTTHUMP00000233475; OTTHUMP00000233900; OTTHUMP00000233473; MGC131774; light polypeptide gene enhancer in B-cells 3, p65 |
Gene ID : | 5970 |
mRNA Refseq : | NM_001145138 |
Protein Refseq : | NP_001138610 |
MIM : | 164014 |
UniProt ID : | Q04206 |
Chromosome Location : | 11q13 |
Pathway : | Activated TLR4 signalling;Acute myeloid leukemia;Angiopoietin receptor Tie2-mediated signaling; B Cell Receptor Signaling Pathway; Cytokine Signaling in Immune system |
Products Types
◆ Recombinant Protein | ||
rela-2736Z | Recombinant Zebrafish rela Protein, His-tagged | +Inquiry |
Rela-5456M | Recombinant Mouse Rela Protein, Myc/DDK-tagged | +Inquiry |
RELA-333H | Recombinant Human NFκB3 (RELA/p65) Protein, Flag-tagged | +Inquiry |
RELA-1878H | Recombinant Human RELA Protein, His (Fc)-Avi-tagged | +Inquiry |
Rela-612M | Recombinant Mouse Rela protein, His & T7-tagged | +Inquiry |
◆ Lysates | ||
RELA-2423HCL | Recombinant Human RELA 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-1652 | HEK 293 RELA Nuclear Translocation Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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