Recombinant Human PTPN9, GST-tagged
Cat.No. : | PTPN9-1857H |
Product Overview : | Recombinant human PTPN9 protein(a.a.285-593) with N-terminal GST tag was expressed in anE.coliexpression system, MW=60.3 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | PTPN9-1857H |
Description : | Tyrosine-protein phosphatase non-receptor type 9 is an enzyme that in humans is encoded by the PTPN9 gene. The protein is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. |
Source : | E.coli. |
Formulation : | 25 mM Tris-HCl, pH 8.0, 75 mM NaCl, 0.05% Tween-20, 50% glycerol, 2 mM EDTA, 1 mM DTT, 10 mM glutathione. |
Purity : | > 70% by SDS-PAGE. |
Specific Activity : | 2 U/ug. One unit will hydrolyze 1 nmol p-nitrophenyl phosphate per minute at pH 7.4 and 30°C. Assay buffer: 50 mM HEPES, pH 7.4, 2 mM EDTA, 3 mM DTT, 100 mM NaCl, 50 mM pNPP. |
Application : | Useful for the study of enzyme kinetics, regulation, to dephosphorylate target substrates and for screening inhibitors. |
Storage : | >6 months at –80°C. |
Gene Name : | PTPN9 protein tyrosine phosphatase, non-receptor type 9 [ Homo sapiens ] |
Synonyms : | protein tyrosine phosphatase, non-receptor type 9; MEG2; PTPMEG2; PTPN9; tyrosine-protein phosphatase non-receptor type 9; PTPase MEG2; PTPase-MEG2; protein-tyrosine phosphatase MEG2; EC 3.1.3.48 |
Gene ID : | 5780 |
mRNA Refseq : | NM_002833 |
Protein Refseq : | NP_002824 |
MIM : | 600768 |
UniProt ID : | P43378 |
Chromosome Location : | 15q24.2 |
Function : | hydrolase activity; non-membrane spanning protein tyrosine phosphatase activity; protein binding; protein tyrosine phosphatase activity |
Products Types
◆ Recombinant Protein | ||
PTPN9-7283M | Recombinant Mouse PTPN9 Protein, His (Fc)-Avi-tagged | +Inquiry |
PTPN9-1300H | Recombinant Human PTPN9 protein(Ala285-Gln593), His&GST-tagged | +Inquiry |
PTPN9-4496R | Recombinant Rat PTPN9 Protein, His (Fc)-Avi-tagged | +Inquiry |
PTPN9-4837R | Recombinant Rat PTPN9 Protein | +Inquiry |
PTPN9-8095H | Recombinant Human PTPN9 protein, His & T7-tagged | +Inquiry |
◆ Lysates | ||
PTPN9-518HCL | Recombinant Human PTPN9 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionGenetic variations in PTPN9 have been associated with altered risk for metabolic diseases.
PTPN9 is a protein tyrosine phosphatase that regulates signal transduction and cellular activity.
PTPN9 is broadly expressed but has higher levels in certain tissues like the liver.
It plays a role in insulin signaling and glucose metabolism, influencing metabolic health.
Therapeutic strategies include developing PTPN9 modulators for cancer and metabolic disorders.
It dephosphorylates substrate proteins, modulating their activity and function.
PTPN9 can act as a tumor suppressor, and its dysregulation is linked to various cancers.
Customer Reviews (3)
Write a reviewReliable product, great results.
Worked well, would recommend.
Quick delivery, excellent product.
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