Active Recombinant Human IL2RA
Cat.No. : | IL2RA-4951H |
Product Overview : | Recombinant Human IL2RA was expressed in insect cells. |
- Specification
- Gene Information
- Related Products
Description : | The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. |
Source : | Insect cells |
Species : | Human |
Form : | Lyophilized from PBS. Reconstitute with PBS, pH 7.2 to a concentration of 0.1 - 1.0 mg/ml. |
Bio-activity : | Determined by its ability to increase the proliferation effect of IL-2 in Mouse CTLL-2 cells. In the presence of 1 ng/ml of recombinant IL-2, the expected ED50 for this effect is between 0.5 - 1.5 ug/ml. |
Molecular Mass : | 31 kDa |
AA Sequence : | ELCDDDPPEI PHATFKAMAY KEGTMLNCEC KRGFRRIKSG SLYMLCTGNS SHSSWDNQCQ CTSSATRNTT KQVTPQPEEQ KERKTTEMQS PMQPVDQASL PGHCREPPPW ENEATERIYH FVVGQMVYYQ CVQGYRALHR GPAESVCKMT HGKTRWTQPQ LICTGEMETS QFPGEEKPQA SPEGRPESET SCLVTTTDFQ IQTEMAATME TSIFTTEYQ. |
Endotoxin : | Endotoxin level is less than 0.1 ng per ug (1 EU/ug). |
Purity : | > 98% pure |
Applications : | User optimized |
Storage : | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
Gene Name : | IL2RA interleukin 2 receptor, alpha [ Homo sapiens (human) ] |
Official Symbol : | IL2RA |
Synonyms : | IL2RA; interleukin 2 receptor, alpha; IL2R; interleukin-2 receptor subunit alpha; CD25; TAC antigen; IL-2R subunit alpha; IL-2 receptor subunit alpha |
Gene ID : | 3559 |
mRNA Refseq : | NM_000417 |
Protein Refseq : | NP_000408 |
MIM : | 147730 |
UniProt ID : | P01589 |
Chromosome Location : | 10p15-p14 |
Pathway : | Arf6 trafficking events; Calcineurin-regulated NFAT-dependent transcription in lymphocytes; Cytokine-cytokine receptor interaction |
Function : | drug binding; interleukin-2 binding; interleukin-2 receptor activity |
Products Types
◆ Recombinant Protein | ||
IL2RA-5197H | Recombinant Human IL2RA Protein | +Inquiry |
IL2RA-43H | Recombinant Human IL2RA Protein, C-Avi&His tagged, Biotinylated | +Inquiry |
IL2RA-5198H | Recombinant Human IL2RA Protein | +Inquiry |
IL2RA-365C | Recombinant Cynomolgus Monkey IL2RA Protein, His (Fc)-Avi-tagged | +Inquiry |
Il2ra-5704M | Active Recombinant Mouse Il2ra protein(Met1-Lys236), hFc-tagged | +Inquiry |
◆ Lysates | ||
IL2RA-1015CCL | Recombinant Cynomolgus IL2RA cell lysate | +Inquiry |
IL2RA-2907HCL | Recombinant Human IL2RA cell lysate | +Inquiry |
IL2RA-2024MCL | Recombinant Mouse IL2RA cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket