Native Human Immunoglobulin Heavy Constant Gamma 1 (G1m marker)

• Cat.No.: IGHG1-617H
• Product Overview: Native human IGHG1 wasexpressed in Human Plasma. Purified from normal serum by immobilizedProtein A. IgG is the most abundant immunoglobulin in plasma, found at aconcentration of 8 to 18 mg/ml.

Specification

• Cat. No.: IGHG1-617H
• Description: Ig gamma-1 chain Cregion is a protein that in humans is encoded by the IGHG1 gene. IgG binds tobacteria and these complexes adhere to phagocytic cells which have surfacereceptors specific for IgG. Prepared from plasma shown to be non reactive forHbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDAapproved tests. >95 percent pure by SDS-PAGE.
• Source: Human Plasma
• Species: Human
• Form: Liquid in 0.02MSodium Phosphate + 0.15M NaCl, pH 7.2.
• Purity: IgG fraction
• Concentration: 10 mg/ml
• Molecular Weight: 160kDa
• Application Notes: The optimalconcentration should be determined by the user for each specific application.
• Storage: When stored at-80°C, product is stable for 3 years from date of delivery.
• OfficialSymbol: IGHG1
• Pathways: Classicalantibody-mediated complement activation; Complement cascade; Creation of C4and C2 activators; IL4-mediated signaling events; Immune System; Initialtriggering of complement; Innate Immune System

Gene Information

• Gene Name: IGHG1 immunoglobulin heavyconstant gamma 1 (G1m marker) [ Homo sapiens ]
• Synonyms: IGHG1;immunoglobulin heavy constant gamma 1 (G1m marker); Ig gamma-1 chain C region
• Gene ID: 3500
• mRNA Refseq: NG_001019
• MIM: 147100
• UniProt ID: P01857
• Chromosome Location: 14q32.32-q32.33
• Function: antigen binding;protein binding