Recombinant Human Interleukin 10, His-tagged
Cat.No. : | IL10-364H |
Product Overview : | Human RecombinantInterleukin-10 produced in E. coli is single, a non-glycosylated, Polypeptidechain containing 160 amino acids fragment (19-178) and having a total MW 18.6kDa with an amino-terminal hexahistidine tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | IL10-364H |
Description : | Interleukin-10(IL-10 or IL10), also known as human cytokine synthesis inhibitory factor(CSIF), is an anti-inflammatory cytokine. In humans IL-10 is encoded by theIL10 gene. This cytokine is produced primarily by monocytes and to a lesserextent by lymphocytes. This cytokine has pleiotropic effects inimmunoregulation and inflammation. It down-regulates the expression of Th1cytokines, MHC class II antigens, and costimulatory molecules on macrophages. |
Source : | E. coli |
Species : | Human |
Form : | Interleukin-10 Hisis supplied in 1 x PBS and 50% glycerol. |
Purity : | Greater than 95.0%as determined by analysis by RP-HPLC and SDS-PAGE. |
Storage : | Store at 2-4°C ifentire vial will be used within 2-4 weeks. Store frozen at -20°C for longerperiods of time. Please avoid freeze-thaw cycles. |
OfficialSymbol : | IL10 |
Pathways : | Africantrypanosomiasis; Allograft rejection; Amoebiasis; Asthma; Autoimmune thyroiddisease; Chagas disease (American trypanosomiasis); Cytokine-cytokine receptorinteraction; Cytokines and Inflammatory Response; IL4-mediated signalingevents; Intestinal immune network for IgA production; Jak-STAT signalingpathway; Leishmaniasis; Malaria; Pertussis; Regulation of nuclear SMAD2/3signaling |
Gene Name : | IL10 interleukin 10 [ Homosapiens ] |
Synonyms : | IL10;interleukin 10; CSIF; TGIF; IL-10; IL10A; MGC126450; MGC126451; interleukin-10;OTTHUMP00000034567; T-cell growth inhibitory factor; cytokine synthesisinhibitory factor ; Interleukin-10; Cytokine synthesis inhibitory factor |
Gene ID : | 3586 |
mRNA Refseq : | NM_000572 |
Protein Refseq : | NP_000563 |
MIM : | 124092 |
UniProt ID : | P22301 |
Chromosome Location : | 1q31-q32 |
Function : | cytokine activity;growth factor activity; interleukin-10 receptor binding |
Products Types
◆ Recombinant Protein | ||
Il10-029I | Active Recombinant Mouse Il10 Protein (161 aa) | +Inquiry |
IL10-2033H | Recombinant Human IL10 Protein, His-tagged | +Inquiry |
Il10-260I | Active Recombinant Rat Il10 Protein | +Inquiry |
IL10-2049R | Recombinant Rhesus Macaque IL10 Protein, His (Fc)-Avi-tagged | +Inquiry |
IL10-262I | Active Recombinant Human IL10 Protein | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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