Native Human Butyrylcholinesterase

• Cat.No.: BCHE-5291H
• Product Overview: Native human BCHEexpressed in Human Serum is a major acetylcholine hydrolyzing enzyme found inthe blood circulation.

Specification

• Cat. No.: BCHE-5291H
• Description: Butyrylcholinesterase (also knownas pseudocholinesterase, plasma cholinesterase, BCHE, or BuChE) is anon-specific cholinesterase enzyme that hydrolyses many different cholineesters. In humans, it is found primarily in the liver and is encoded by the BCHEgene. Butyrylcholine is a synthetic compound and does not occur in the bodynaturally. It is used as a tool to distinguish between acetyl- and BCHE.
• Form: Lyophilized from0.02 M NH4HCO3 Buffer.
• Source: Human Serum
• Biological Activity: > 100 U/mgprotein. One unit will hydrolyze 1.0 µmole of butyrylcholine to choline andbutyrate per minute at pH 8.0 at 37°C.
• Storage: Store at -20°C.Stable for 1 year. Avoid repeated freeze-thaw cycles.
• Pathways: Diabetes pathways; Irinotecan Pathway;Synthesis

Gene Information

• Gene Name: BCHE butyrylcholinesterase [ Homosapiens ]
• Official Symbol: BCHE
• Synonyms: BCHE;butyrylcholinesterase; E1; CHE1; cholinesterase; cholinesterase 1;OTTHUMP00000212636; choline esterase II; pseudocholinesterase; butyrylcholineesterase; acylcholine acylhydrolase
• Gene ID: 590
• mRNA Refseq: NM_000055
• Protein Refseq: NP_000046
• MIM: 177400
• UniProt ID: P06276
• Chromosome Location: 3q26.1-q26.2
• Function: acetylcholinesteraseactivity; beta-amyloid binding; carboxylesterase activity; catalyticactivity; choline binding; cholinesterase activity; enzyme binding; hydrolaseactivity