"BCHE" Related Products

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Native Human Butyrylcholinesterase

Cat. No.: BCHE-5291H
Product Overview: Native human BCHEexpressed in Human Serum is a major acetylcholine hydrolyzing enzyme found inthe blood circulation.
Description: Butyrylcholinesterase (also knownas pseudocholinesterase, plasma cholinesterase, BCHE, or BuChE) is anon-specific cholinesterase enzyme that hydrolyses many different cholineesters. In humans, it is found primarily in the liver and is encoded by the BCHEgene. Butyrylcholine is a synthetic compound and does not occur in the bodynaturally. It is used as a tool to distinguish between acetyl- and BCHE.
Form: Lyophilized from0.02 M NH4HCO3 Buffer.
Source: Human Serum
Biological Activity: > 100 U/mgprotein. One unit will hydrolyze 1.0 µmole of butyrylcholine to choline andbutyrate per minute at pH 8.0 at 37°C.
Storage: Store at -20°C.Stable for 1 year. Avoid repeated freeze-thaw cycles.
Pathways: Diabetes pathways; Irinotecan Pathway;Synthesis
Gene Name: BCHE butyrylcholinesterase [ Homosapiens ]
Official Symbol: BCHE
Synonyms: BCHE;butyrylcholinesterase; E1; CHE1; cholinesterase; cholinesterase 1;OTTHUMP00000212636; choline esterase II; pseudocholinesterase; butyrylcholineesterase; acylcholine acylhydrolase
Gene ID: 590
mRNA Refseq: NM_000055
Protein Refseq: NP_000046
MIM: 177400
UniProt ID: P06276
Chromosome Location: 3q26.1-q26.2
Function: acetylcholinesteraseactivity; beta-amyloid binding; carboxylesterase activity; catalyticactivity; choline binding; cholinesterase activity; enzyme binding; hydrolaseactivity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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