Recombinant Rabbit Serpin Peptidase Inhibitor, Clade E (nexin, plasminogen activator inhibitor type 1), Member 1

• Cat.No.: SERPINE1-1866R
• Product Overview: Thisstable mutant of rabbit SERPINE1 contains a singleconservative mutation (Isoleucine 91 to Leucine) that yields PAI-1 with anenhanced half-life as compared to the wild type.

Specification

• Cat. No.: SERPINE1-1866R
• Description: SERPINE1 is aprotein that in humans is encoded by the SERPINE1 gene. SERPINE1 is a serineprotease inhibitor (serpin) thatfunctions as the principal inhibitor of tissue plasminogen activator (tPA)and urokinase (uPA), the activators of plasminogen and hence fibrinolysis(the physiological breakdown of blood clots). It is a serine proteaseinhibitor (serpin) protein (SERPINE1).
• Source: E. coli
• Species: Rabbit
• Concentration: 2.5mg/ml
• Form: Liquidin 0.05 M Sodium Acetate + 0.1M NaCl + 1mM EDTA, pH 5.0.
• Purity: >95% by SDS-PAGE.
• Molecular Weight: 43 kDa
• Endotoxin Level: <0.1 ng/μg of protein.
• Specific Activity: 80%active by titration with tPA.
• Storage: Storeat -80°C. Stable for 3years from delivery. For long term use, divide into working aliquots andfreeze at -80°C. Avoid repeatedfreeze-thaw cycles.
• OfficialSymbol: SERPINE1

Gene Information

• Gene Name: SERPINE1 serpin peptidaseinhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1[ Oryctolagus cuniculus ]
• Synonyms: SERPINE1; serpinpeptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1),member 1; putative plasminogen activator inhibitor-1
• Gene ID: 100009588
• mRNA Refseq: XM_002722823
• Protein Refseq: XP_002722869