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Recombinant Human UBE2D3

Cat.No. : UBE2D3-1882H
Product Overview : Recombinant Human UBE2D3 was expressed inE.Coli.
  • Specification
  • Gene Information
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Cat. No. : UBE2D3-1882H
Description : UBE2D3 enzymes are human homologs of the yeast UBC4/5 family and play many important regulatory roles in inflammation and cancer. UbcH5a mediates the degradation of a myriad of short-lived regulatory proteins (such as p53 in the presence of E6/E6-AP or MDM2, c-Fos, IκBα, p105) and abnormal proteins. UBE2D3 has 88% and 89% sequence identity with UbcH5a and UbcH5b respectively.
Source : Escherichia Coli.
Amino Acid Sequence : MHHHHHHAM ALKRINKELSDLA RDPPAQCSAGPV GDDMF HWQATIMGP NDSPYQGGVFFLTIHFPTD YPFKPPKVAFTTRIY HPNINSNGSI CLDILRS QWSPALTISK VLLSICSLLCDPNPDDPL.
Physical Appearance : Sterile Filtered white lyophilized powder.
Purity : Greater than 95.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Formulation : Lyophilized from a 0.2μm filtered concentrated (1 mg/ml) solution in 1X PBS and 1mM DTT, pH 7.5.
Stability : Lyophilized UBE2D3 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution UBE2D3 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Gene Name : UBE2D3 ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) [ Homo sapiens ]
Synonyms : ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast); UBC4/5; UBCH5C; MGC5416; MGC43926; E2(17)KB3; UBE2D3; ubiquitin-conjugating enzyme E2 D3; E2(17)KB 3; ubiquitin-protein ligase D3; ubiquitin carrier protein D3; ubiquitin-conjugating enzyme E2-17 kDa 3;ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC4/5); Ubiquitin-conjugating enzyme E2-17 kDa 3; UbcH5C; EC 6.3.2.19; Ubiquitin-protein ligase D3; Ubiquitin carrier protein D3
Gene ID : 7323
mRNA Refseq : NM_003340.5
Protein Refseq : NP_003331.1
MIM : 602963
UniProt ID : P61077
Chromosome Location : 4q24
Pathway : Ubiquitin mediated proteolysis; Signaling by BMP; Signaling by TGF beta
Function : ATP binding; ligase activity; nucleotide binding; protein binding; ubiquitin-protein ligase activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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